Comparison of photodynamic treatment produced cell damage between human breast cancer cell MCF-7 and its multidrug resistance cell

Wang Haiping; Li Long; Wang Pan; Wang Xiaobing; Zhang Kun; Liu Quanhong

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Comparison of photodynamic treatment produced cell damage between human breast cancer cell MCF-7 and its multidrug resistance cell

机译：光动力治疗产生的人乳腺癌细胞MCF-7及其多药耐药细胞的细胞损伤比较

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Background: Multidrug resistance (MDR) of breast cancer is a major obstacle in chemotherapy of cancer treatments. Recently the anti-tumor effects of Chlorin e6 (Ce6) mediated photodynamic therapy (Ce6-PDT) were reported in skin cancer and hepatoma in vitro. However, its therapeutic potential in killing human breast cancer especially those with MDR and the differences between MCF-7 and MCF-7/ADR after PDT treatment has not been fully investigated.

机译：背景：乳腺癌的多药耐药性（MDR）是癌症治疗化学疗法的主要障碍。最近，在皮肤癌和肝癌中报道了氯霉素e6（Ce6）介导的光动力疗法（Ce6-PDT）的抗肿瘤作用。但是，尚未完全研究其在杀死人乳腺癌尤其是具有MDR的乳腺癌中的治疗潜力以及PDT治疗后MCF-7和MCF-7 / ADR之间的差异。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2016年第12期|1-8|共8页
作者
Wang Haiping; Li Long; Wang Pan; Wang Xiaobing; Zhang Kun; Liu Quanhong;
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作者单位

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

Shaanxi Normal Univ, Key Lab, Minist Educ Med Plant Resources & Nat Pharmaceut, Coll Life Sci, Xian, Shaanxi, Peoples R China;

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正文语种 eng
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关键词
Adriamycin resistant cell; MCF-7; Ce6-PDT; Apoptosis; Autophagy;

机译：阿霉素耐药细胞;MCF-7;Ce6-PDT;细胞凋亡;自噬;

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专利

1. Comparison of the properties of human breast cancer cells: MCF-7 and MCF-7 cells selected for resistance to etoposide. [J] . Cory AH, Cory JG Advances in enzyme regulation . 2001,第0期

机译：人类乳腺癌细胞特性的比较：选择对依托泊苷具有抗性的MCF-7和MCF-7细胞。
2. Comparison of cell membrane damage induced by the therapeutic ultrasound on human breast cancer MCF-7 and MCF-7/ADR cells [J] . Jia Yali, Yuan Wenjuan, Zhang Kun, Ultrasonics sonochemistry . 2015,第Null期

机译：治疗性超声波对人乳腺癌MCF-7和MCF-7 / ADR细胞的细胞膜损伤的比较
3. MCF-7/ADR cells (re-designated NCI/ADR-RES) are not derived from MCF-7 breast cancer cells: a loss for breast cancer multidrug-resistant research. [J] . Ke W, Yu P, Wang J, Medical oncology . 2011,第Suppla1期

机译：MCF-7 / ADR细胞（重新指定为NCI / ADR-RES）并非源自MCF-7乳腺癌细胞：对乳腺癌多药耐药性研究的损失。
4. Overcoming Multidrug Resistance of Breast Cancer Cells by the Micellar Drug Carriers of mPEG-PCL-graft-cellulose [C] . Yung-Tsung Chen, Chao-Hsuan Chen, Ming-Fa Hsieh International Conference on Biomedical Engineering . 2008

机译：MPEG-PCL-移植纤维素的胶束药物载体克服乳腺癌细胞的多药耐药性
5. Photofrin-mediated electroporation-assisted photodynamic therapy of MCF-7 human breast cancer and B16-F10 mouse melanoma cells. [D] . Huffman, David P. 2011

机译：Photofrin介导的MCF-7人乳腺癌和B16-F10小鼠黑素瘤细胞的电穿孔辅助光动力疗法。
6. Atg7 deficiency increases resistance of MCF-7 human breast cancer cells to photodynamic therapy [O] . Liang-yan Xue, Song-mao Chiu, Nancy L. Oleinick -1

机译：ATG7缺乏增加MCF-7人乳腺癌细胞对光动力治疗的抗性
7. A shift from normal to high glucose levels stimulates cell proliferation in drug sensitive MCF-7 human breast cancer cells but not in multidrug resistant MCF-7/ADR cells which overproduce PKC-?II [O] . Mayumi Yamamoto, Niketa A. Patel, Jennifer Taggart, 1999

机译：从正常到高葡萄糖水平的偏移刺激药物敏感MCF-7人乳腺癌细胞中的细胞增殖，但不在多药抗性MCF-7 / ADR细胞中，其过度提出PKC-？II

Comparison of photodynamic treatment produced cell damage between human breast cancer cell MCF-7 and its multidrug resistance cell

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