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Veterinary photodynamic therapy: A review

机译:兽医光动力疗法:综述

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摘要

Whereas in human medicine photodynamic therapy represents a well-known and recognized treatment option for diverse indications, it is still little known and unfortunately not yet established treatment option for pets. Various photosensitizers and light sources have been used and clinical results have been published. The main indication is a frequently occurring skin tumor in cats: in situ carcinoma/squamous cell carcinoma, mainly found in not or only slightly pigmented areas of the head. For early stages of this tumor, promising results have been published, partly using new, selective drugs to decrease light sensitivity after systemic administration and to increase response rates. Other possible indications are urinary tract neoplasia of dogs and equine sarcoids, the latter representing very common tumors in horses where no effective treatment is known so far. This review article summarizes the role of photodynamic therapy in veterinary medicine.
机译:尽管在人类医学中,光动力疗法代表了多种适应症的众所周知且公认的治疗选择,但它仍然鲜为人知,遗憾的是尚未建立宠物的治疗选择。已经使用了各种光敏剂和光源,并且已经发表了临床结果。主要适应症是猫中经常发生的皮肤肿瘤:原位癌/鳞状细胞癌,主要存在于头部的色素沉着区域,或仅在色素沉着的区域。对于该肿瘤的早期阶段,已经发表了令人鼓舞的结果,部分使用新的选择性药物来降低全身给药后的光敏性并提高反应率。其他可能的适应症是狗的尿路肿瘤和马类肌瘤,后者代表了目前尚无有效治疗方法的马中非常常见的肿瘤。这篇综述文章总结了光动力疗法在兽医学中的作用。

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