Surgical debulking combined with photodynamic therapy to manage residual extramedullary plasmacytoma of the nasopharynx

Baris Karakutlukcu; Jan Paul De Boer; Robert Van Veen; Jurgen Wegman; Bing Tan

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Surgical debulking combined with photodynamic therapy to manage residual extramedullary plasmacytoma of the nasopharynx

机译：手术减体联合光动力疗法治疗鼻咽残留髓外浆细胞瘤

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Extramedullary plasmacytomas (EMP) are rare plasma cell neoplasms that are mostly located in the mucosal surfaces of the upper aerodigestive tract. The standard treatment is radiotherapy (RT), with surgical resection reserved as salvage procedure. In this report a patient with a EMP, located in the nasopharynx and refractory to curative RT. Because of the technical difficulty of a radical resection in the nasopharynx area the EMP is managed by endoscopic debulking and temoporfin mediated photodynamic therapy. The patient remains disease free since six years.

机译：髓外浆细胞瘤（EMP）是稀有的浆细胞瘤，多数位于上消化道的粘膜表面。标准治疗是放疗（RT），保留手术切除作为抢救程序。在本报告中，一名患有EMP的患者位于鼻咽部，难以治愈的RT。由于鼻咽区域根治性切除术的技术难度，EMP通过内窥镜减灭术和替莫泊芬介导的光动力疗法进行管理。该患者自六年以来一直没有疾病。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2011年第3期|p.264-266|共3页
作者
Baris Karakutlukcu; Jan Paul De Boer; Robert Van Veen; Jurgen Wegman; Bing Tan;
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作者单位

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands;

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands;

Erasmus University Medical Center, Center of Optical Diagnosis and Therapy, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands;

Deventer Hospital, Nico Bolkesteinlaan 75, Deventer, The Netherlands;

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands;

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正文语种 eng
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关键词
Extramedutlary plasmacytoma; Photodynamic therapy; Nasopharynx;

机译：髓外浆细胞瘤;光动力疗法;鼻咽;

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2. An Extramedullary Plasmacytoma of the Nasopharynx : A rare entity [J] . Abdul Mokhti Abdullah, Zambri Ibrahim, Zulkifli Yusuf, Bangladesh Journal of Medical Science . 2016,第3期

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3. Unusual coexistence of extramedullary plasmacytoma and nasopharyngeal carcinoma in nasopharynx [J] . Ri-chang Du, Hai-nan Li, Wei Huang, Diagnostic pathology . 2015,第S1期

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6. Extramedullary Solitary Plasmacytoma with Anaplastic Features of the Nasopharynx [O] . Parikshit Padhi, Radwa El-Behery 2020

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Surgical debulking combined with photodynamic therapy to manage residual extramedullary plasmacytoma of the nasopharynx

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