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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Salvage photodynamic therapy for extended carcinoma in situ of the oesophagus after subtotal oesophagectomy: 2 years follow up
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Salvage photodynamic therapy for extended carcinoma in situ of the oesophagus after subtotal oesophagectomy: 2 years follow up

机译：食管癌次全切除术后食管原位癌的抢救光动力治疗：2年随访

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摘要

The incidence of oesophageal cancer continuously increases and 400000 new cases/year are diagnosed worldwide. Total oesophagectomy is recommended when multifocal disease, especially in case of Barrett's oesophagus [1]. However, selected cases may benefit from subtotal oesophagectomy, with 5-year survival rates ranging from 20% to 50% [1]. Local recurrence after subtotal oesophagectomy is relatively high (30-40%) and regular endoscopic surveillance is mandatory. Early stage lesions are eligible for endoscopic minimally invasive surgery such as endoscopic mucosai resection or dissection (EMR, EMD), argon plasma photocoagulation, radiofrequency ablation or photodynamic therapy (PDT). Photodynamic therapy is now commonly applied to eradicate dysplasia and Barrett's oesophagus but can also achieve destruction of squamous cell carcinoma. In the present paper, we report a case of multifocal high grade dysplasia, in a patient with prior subtotal oesophagectomy, treated with PDT.
机译：食道癌的发病率持续增加，全世界每年诊断出40万例新病例。当发生多灶性疾病时，尤其是在Barrett食道的情况下，建议进行全食管切除术[1]。但是，部分病例可能会从全切食管切除术中受益，其5年生存率在20％至50％之间[1]。食管全切术后局部复发率较高（30-40％），必须定期进行内镜检查。早期病变适合于内镜微创手术，例如内镜黏膜切除术或剥离术（EMR，EMD），氩等离子体光凝，射频消融或光动力疗法（PDT）。现在，光动力疗法通常用于根除不典型增生和巴雷特食管，但也可以破坏鳞状细胞癌。在本论文中，我们报道了一例接受PDT治疗的食管癌次全切除术的多灶性高度不典型增生。

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