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Scope of antimicrobial photodynamic therapy in Orthodontics and related research: A review

机译：正畸抗菌光动力疗法的范围及相关研究综述

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摘要

Background: The aim of the present study was to comprehensively review indexed literature regarding the potential role of antimicrobial photodynamic therapy (aPDT) in Orthodontics.Methods: Indexed databases were searched up to and including January 2019 using the following key words: (a) antimicrobial photodynamic therapy; (b) antimicrobial photodynamic chemotherapy; (c) orthodontic; and (d) orthodontics. Original (clinical and experimental) studies, case-reports, and case-series were included. Letters to the Editor, commentaries and review articles were excluded.Results: Out of the 29 studies identified in the initial search, 4 studies were processed for data extraction. Three studies were randomized clinical trials performed in humans and 1 study was experimental. Results from 2 studies showed that aPDT is effective in the treatment of gingival inflammation in patients undergoing orthodontic therapy (OT). One study showed that oral decontamination can be successfully performed using aPDT among patients undergoing OT. Results of the experimental study showed that aPDT helps in surface decontamination of orthodontic instruments.Conclusion: There is insufficient evidence in indexed literature to justify the potential role of aPDT in OT. Hence, further studies are required in this regard.
机译：背景：本研究的目的是全面审查索引文献，以了解抗菌光动力疗法（aPDT）在正畸中的潜在作用。方法：使用以下关键词对截至2019年1月（含）的索引数据库进行搜索：（a）抗菌药物光动力疗法； （b）抗菌光动力化学疗法； （c）正畸； （d）正畸。包括原始（临床和实验）研究，病例报告和病例系列。结果：在最初搜索中确定的29项研究中，有4项研究被处理以提取数据。三项研究是在人类中进行的随机临床试验，而一项研究是实验性的。两项研究的结果表明，aPDT对正畸治疗（OT）患者的牙龈炎症有效。一项研究表明，使用aPDT可以在接受OT的患者中成功进行口腔净化。实验研究结果表明，aPDT有助于牙齿正畸器械的表面净化。结论：索引文献中没有足够的证据证明aPDT在OT中的潜在作用。因此，在这方面需要进一步的研究。

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