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Photobiomodulation and antimicrobial photodynamic therapy as adjunct in the treatment and prevention of osteoradionecrosis of the jaws: A case report

机译:PhotobioModulation和抗微生物的光动力治疗作为治疗和预防颌骨成骨坏死的辅助疗法:案例报告

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Case report: We report on a patient with a history of radiotherapy to the head and neck region exhibiting necrotic bone exposure associated with fistula and purulent exudation in the mandible, with the diagnosis of stage 3 osteoradionecrosis, in addition to a periapical cyst in the maxillary anterior region and multiple root remnants. An antibiotic coverage protocol with amoxicillin and metronidazole was prescribed for subsequent necrotic bone removal. The surgical procedure was performed along with the aPDT using methylene blue and red light, followed by coaptation of the edges of the surgical wound and the healing protocol with LLLT. The extraction of non-rehabilitated teeth was performed two per session using antibiotic coverage, aPDT, and LLLT and mouthwash with 0.12 % chlorhexidine was prescribed until the complete closure of the surgical wound was achieved. Additionally, two aPDT sessions and four LLLT protocols were performed for complete healing of the surgical sites. Extra and intraoral examinations and panoramic and periapical radiographs were performed. No emergence or recurrence of osteonecrosis was observed after 12 months of follow-up.
机译:案例报告:我们向头部和颈部区域报告患者,表现出与瘘管相关的坏死骨暴露和下颌骨的脓性渗出,随着阶段3骨草坏死的诊断,除了上颌中的围绕囊肿前区域和多根遗留。抗生素覆盖方案具有阿莫西林和甲硝唑的抗生素覆盖方案,用于随后的坏死骨去除。使用亚甲蓝和红光与APDT进行外科手术,然后进行外科伤口边缘和LLTT的愈合方案的凋亡。每次使用抗生素覆盖,APDT和LLLT和LLLT和漱口水进行两次进行两次恢复牙齿的提取,并规定了0.12%氯己定,直到达到了手术伤口的完全闭合。此外,对手术部位的完全愈合进行了两种APDT会话和四个LLLT协议。进行额外和内部检查和全景和恐慌的射线照片。在随访12个月后,没有观察到骨折的出现或复发。

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