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Outcome of photodynamic therapy on orthodontic leveling and alignment of mandibular anterior segment: A controlled clinical trial

机译:光动力治疗对正畸水平的结果及下颌前段的对准:受控临床试验

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Background: Photodynamic therapy (PDT) is a non-invasive approach that has drawn attention to accelerate orthodontic tooth movement (OTM). However, no studies have been published that evaluates the outcome of PDT on orthodontic leveling and alignment. Therefore, the present study aimed to evaluate outcome of PDT on orthodontic leveling and alignment of mandibular anterior segment.Materials and methods: Thirty patients (18 females and 12 males) were included who had moderate mandibular crowding with average age was 19.23 +/- 3.1 years. They were randomly divided into a control group without PDT intervention and a laser group. All patients followed non-extraction approach using one category of fixed appliance and matching NiTi archwire sequence for 3 months. In PDT group, methylene blue mediated gallium aluminum arsenide laser was applied with 635 nm, 6.5 J/cm(2), for 10 s at 10 points (0.2 J/point) started immediately after first wire then at days 3,7,14 of first month and repeated for additional 2 months. Relief of crowding was assessed by Little's irregularity index (LII) scores after 4, 8, and 12 weeks through scanned 3-dimensional models via a software.Results: Both groups showed improvements in mandibular crowding as evidenced by significant decreases (p = 0.001) in LII scores during all observation intervals with no significant differences (p 0.05). Moreover, the alignment's rate showed no significant differences between groups.Conclusion: PDT produced a negligible effect concerning alignment of crowded mandibular anterior teeth. Besides, OTM's rate at different observation intervals showed an equivalent pattern either with or without PDT.
机译:背景:光动力疗法(PDT)是一种非侵入性方法,引起了加速正畸牙齿运动(OTM)。然而,没有发表研究,评估PDT在正畸水平和对准中的结果。因此,本研究旨在评估PDT对颌骨闭合细胞的矫正性和对准的结果。和方法:30例患者(18名女性和12名男性),平均年龄为19.23 +/- 3.1,包括中度下颌挤在一起年。它们被随机分为没有PDT干预和激光组的对照组。所有患者遵循非提取方法,使用一类固定设备和匹配NITI archwire序列3个月。在PDT组中,亚甲基蓝介导镓铝砷化铝激光器施用635nm,6.5克/厘米(2),10秒,在第一线后立即启动10点(0.2 j / poix),然后在第3,7,14天后立即开始第一个月并重复2个月。通过软件扫描的三维模型,在4,8和12周后,通过扫描的三维模型在4,8和12周后评估拥挤的救济。结果:两组在下颌挤出的改善,如显着降低所证明的(P <= 0.001 )在所有观察间隔内的LII分数没有显着差异(p> 0.05)。此外,对准的速率在组之间没有显着差异。结论:PDT在拥挤的下颌骨前齿的对齐产生了可忽略的效果。此外,OTM以不同观察间隔的速率显示在或没有PDT的等效图案。

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