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Photodynamic therapy and subthreshold micropulse laser treatment - A novel combined approach for the treatment of serous retinal detachment i dome-shaped macula

机译：光动力疗法和亚阈值微型激光治疗 - 一种治疗浆膜视网膜脱离的新型综合方法I圆顶形斑疹

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摘要

Dome-shaped macula (DSM) is characterized by an inward convexity of the macula in myopic eyes, as visualized on optical coherence tomography (OCT). Serous retinal detachment (SRD) is a common complication of DSM, leading to a deterioration of visual acuity, in association with retinal pigment epithelium (RPE) atrophic changes. Many different therapeutic approaches to SRD secondary to DSM have been attempted, with variable results. We report our experience (11 treatment-naive patients) with a combined new treatment approach, using half-fluence and half-dose photodynamic therapy (PDT) followed by subthreshold 577 nm micropulse laser treatment (STLT), for SRD related to DSM after a 6-month follow-up. Central foveal thickness was significantly decreased at the end of the follow-up. SRD diminished in all cases, and 5 eyes (45.4 %) registered complete resolution at the end of the 6-month follow-up, while 6 eyes (54.5 %) experienced two lines of improvement in BCVA at the end of the follow-up. No case showed postoperative complications. Therefore, this represents the first study evaluating the visual and anatomical outcomes of a safe and effective combined treatment of SRD in DSM.
机译：圆顶形状的黄斑（DSM）的特征在于近视眼中的黄斑的向内凸起，如光学相干断层扫描（OCT）上的可视化。浆液视网膜脱离（SRD）是DSM的常见并发症，导致视力的劣化，与视网膜色素上皮（RPE）萎缩变化相关联。已经尝试了许多不同的治疗方法对DSM次级的SRD进行了可变结果。我们向多种新的治疗方法报告我们的经验（11名治疗 - 幼稚患者），使用半量流量和半剂量光动力治疗（PDT），然后是亚阈值577nm微型激光治疗（STLT），用于达姆之后的SRD。 6个月的随访。在随访结束时，中央芯片厚度显着降低。所有病例减少，5只眼（45.4％）在6个月后续随访结束时注册了完整的决议，而6只眼（54.5％）在后续行动结束时经历过两条改进。没有案例显示术后并发症。因此，这代表了第一研究评估了DSM中安全有效的SRD的安全有效联合治疗的视觉和解剖结果。

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