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Antimicrobial effect of photodynamic therapy on intracanal biofilm: A systematic review of in vitro studies

机译：光动力疗法对颅内生物膜的抗菌疗效：体外研究的系统综述

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Background: Antimicrobial photodynamic therapy (A-PDT), is one of the adjunctive therapies developed to improve the effectiveness of root canal disinfection.. The aim of this study was to analyze the antimicrobial effect of PDT on intracanal biofilm.Methods: Two reviewers conducted a literature search in PubMed, MEDLINE, Lilacs, SciELO, EMBASE and Google Scholar using the following search strategy: photochemotherapy "[Mesh] OR (photodynamic therapy) AND" dental plaque "[Mesh] OR (dental biofilm) AND (root canal). The following data were collected: publication year, author's name, study site, type of study, participant number, type of photosensitizer, type of laser, method of data collection, application time and results. Study quality was assessed using the Methodological Index for Non Randomized Studies (MINORS).Results: After selection based on title, abstract and full text, 27 studies were included in this systematic review. PDT reduced bacterial viability in most studies when combined with conventional endodontic techniques.Conclusion: PDT reduced bacterial counts in most studies, especially when used as an adjunct to the conventional endodontic technique to treat refractory infection. However, PDT effects on in vitro bacterial biofilm were not accurately quantified because of the numerous biases in the studies reviewed.
机译：背景：抗微生物光动力治疗（A-PDT）是为提高根管消毒的有效性而开发的辅助疗法。本研究的目的是分析PDT对植物生物膜的抗微生物作用。方法：两次审查员进行了两种审稿人使用以下搜索策略的PubMed，Medline，Lilacs，Scielo，Embase和Google Scholar的文献搜索：Photochemotherapy“[网格]或（光动力学疗法）和”牙科斑纹“[网格]或（牙科生物膜）和（根管） 。收集以下数据：发布年份，作者姓名，学习网站，学习类型，参与者编号，光敏剂类型，激光类型，数据收集方法，应用时间和结果。使用方法指数评估研究质量非随机研究（未成年人）。结果：基于标题的选择后，摘要和全文，27项系统综述综合作用。PDT降低了大多数研究时的细菌活力常规牙髓技术。结论：PDT在大多数研究中减少细菌计数，特别是当用作常规牙髓技术的辅助治疗难治性感染时。然而，由于研究中的许多偏差，因此不准确地量化对体外细菌生物膜的PDT作用。

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