Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

L. Zhou; A. Schnitzler; J. Agapite

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Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

机译：果蝇中枢神经系统中线细胞程序性死亡中收割者和头部对合缺陷基因的协同功能

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In Drosophila, the chromosomal region 75C1-2 contains at least three genes, reaper (rpr), head involution defective (hid), and grim, that have important func- tions in the activation of programmed cell death. To better understand how cells are killed by these genes, we have utilized a well defined set of embryonic central nervous system midline cells that normally exhibit a specific pattern of glial cell death. In this study we show that both rpr and hid are expressed in dying midline cells and that the normal pattern of midline cell death requires the function of multiple genes in the 75C1-2 interval.

机译：在果蝇中，染色体区域75C1-2包含至少三个基因，即收割者（rpr），头部对合缺陷（hid）和严峻，它们在激活程序性细胞死亡的激活中具有重要的功能。为了更好地了解这些基因如何杀死细胞，我们利用了一组定义明确的胚胎中枢神经系统中线细胞，这些细胞通常表现出特定的神经胶质细胞死亡模式。在这项研究中，我们显示rpr和hid均在垂死的中线细胞中表达，并且中线细胞死亡的正常模式需要在75C1-2间隔中具有多个基因的功能。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第10期|p.5131-5136|共6页
作者
L. Zhou; A. Schnitzler; J. Agapite;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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机译：严峻的程序性细胞死亡在果蝇胚胎发生和变态过程中建立corazonin产生的肽能神经系统中的重要作用严峻的程序性细胞死亡在果蝇的胚胎发生和变形过程中建立corazonin产生的肽能神经系统中的重要作用。果蝇致死的程序性细胞死亡在果蝇胚胎发生和变态过程中建立可乐宁生产肽能神经系统的建立中的重要作用
2. Expression of the apoptosis inducer gene head involution defective in primordial germ cells of the Drosophila embryo requires eiger, p53, and loki function [J] . Maezawa T, Arita K, Shigenobu S, Development Growth and Differentiation . 2009,第4期

机译：果蝇胚胎原始生殖细胞中凋亡诱导基因头部向内缺陷的表达需要eiger，p53和loki功能
3. The CNS midline cells and Egfr signaling genes are required for establishment of the RP2 motoneuron lineage in the Drosophila central nervous system. [J] . Huh JY, Jeon SH, Kim SH Biochemical and Biophysical Research Communications . 2009,第4期

机译：在果蝇中枢神经系统中建立RP2运动神经元谱系需要CNS中线细胞和Egfr信号基因。
4. Cytological features of programmed cell death in Nicotiana tabacum cells in relation tothe expression and localization of death regulators [C] . Louise Brisson, Nathalie Bolduc, Mario Ouellet, Microscopy Society of America annual meeting;Microscopy Society of Canada annual meeting;Societe de Microscopie du Canada annual meeting;Microbeam Analysis Society annual meeting;International Metallographic Society annual meeting . 2002

机译：烟草细胞中程序性细胞死亡的细胞学特征与死亡调节因子的表达和定位有关
5. The control of gene expression in the Drosophila central nervous system midline cells and the function of the single-minded gene [D] . Mosher, Jack Thomas. 2001

机译：果蝇中枢神经系统中线细胞基因表达的控制和一心一意基因的功能
6. Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells [O] . L. Zhou, A. Schnitzler, J. Agapite, 1997

机译：果蝇中枢神经系统中线细胞的程序性细胞死亡中收割者和头部对合缺陷基因的协同功能
7. Erratum: Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes [O] . JP Wing, L Zhou, LM Schwartz, 1999

机译：错误：不同细胞杀死果蝇收割机，头部缺陷和严峻基因的细胞杀伤性质

Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

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