Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart

Jolanta Gutkowska; Marek Jankowski; Chantal Lambert

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Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart

机译：催产素通过与心脏中的催产素受体结合释放心钠素

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Previous studies indicated that the central nervous system induces release of the cardiac hormone atrial natriuretic peptide (ANP) by release of oxytocin from the neurohypophysis. The presence of specific transcripts for the oxytocin receptor was demonstrated in all chambers of the heart by amplification of cDNA by the PCR using specific oligonucleotide primers. Oxytocin receptor mRNA content in the heart is 10 times lower than in the uterus of female rats. Oxytocin receptor transcripts were demonstrated by in situ hybridization in atrial and ventricular sections and confirmed by competitive binding assay using frozen heart sections.

机译：以前的研究表明，中枢神经系统通过从神经垂体释放催产素来诱导心脏激素心钠素释放。通过使用特异性寡核苷酸引物通过PCR扩增cDNA，证明了催产素受体特异性转录物的存在。心脏中催产素受体mRNA的含量比雌性大鼠子宫低10倍。催产素受体转录本通过在心房和心室切片中的原位杂交得到证实，并通过使用冷冻心脏切片的竞争性结合试验得以证实。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第21期|p.11704-11709|共6页
作者
Jolanta Gutkowska; Marek Jankowski; Chantal Lambert;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Neonatal oxytocin treatment modulates oxytocin receptor, atrial natriuretic peptide, nitric oxide synthase and estrogen receptor mRNAs expression in rat heart. [J] . Pournajafi-Nazarloo H, Perry A, Partoo L, Peptides: An International Journal . 2007,第6期

机译：新生儿催产素治疗可调节大鼠心脏中的催产素受体，心钠素，一氧化氮合酶和雌激素受体mRNA的表达。
2. Central nitric oxide blocks vasopressin, oxytocin and atrial natriuretic peptide release and antidiuretic and natriuretic responses induced by central angiotensin II in conscious rats. [J] . Reis WL, Giusti-Paiva A, Ventura RR, Experimental Physiology . 2007,第5期

机译：中枢一氧化氮可阻断清醒大鼠中血管加压素，催产素和心钠素的释放，以及中枢血管紧张素II诱导的抗利尿和利尿钠反应。
3. Nitric oxide acutely modulates hypothalamic and neurohypophyseal carbon monoxide and hydrogen sulphide production to control vasopressin, oxytocin and atrial natriuretic peptide release in rats [J] . Coletti Ricardo, Lima Juliana Bezerra Medeiros, Vechiato Fernanda Maria Veanholi, Journal of neuroendocrinology . 2019,第2期

机译：一氧化氮急性调节下丘脑和神经内肌肌型一氧化碳和硫化氢产生，以控制大鼠的血压加强素，催产素和心房利尿尿肽释放
4. Identification of a receptor for annetocin,invertebrate oxytocin/vasopressin superfamily peptide [C] . Tsuyoshi Kavvada, Atsuhiro Kanda, Hiroyuki Minakata International Peptide Symposium;European Peptide Symposium . 2005

机译：鉴定annetocin的受体，无脊椎催产素/血管加压素超家族肽
5. Atrial natriuretic peptide receptor subtype determination and biological actions of atrial natriuretic peptide in bovine cardiac muscle and hypertensive rat liver [D] . McCartney, Shirley. 1992

机译：心钠素受体亚型的测定及其在牛心肌和高血压大鼠肝脏中的作用
6. Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart [O] . Jolanta Gutkowska, Marek Jankowski, Chantal Lambert, 1997

机译：催产素通过与心脏中的催产素受体结合释放心钠素
7. Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart [O] . J. Gutkowska, M. Jankowski, C. Lambert, 1997

机译：催产素通过与心脏中的催产素受体组合来释放心房钠尿肽

Oxytocin releases atrial natriuretic peptide by combining with oxytocin receptors in the heart

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