...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Electrophysiological studies on rat dorsal root ganglion neurons after peripheral axotomy: Changes in responses to neuropeptides
【24h】

Electrophysiological studies on rat dorsal root ganglion neurons after peripheral axotomy: Changes in responses to neuropeptides

机译：周围轴切术后大鼠背根神经节神经元的电生理研究：对神经肽反应的变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The effect of three peptides, galanin, sulfated cholecystokinin octapeptide, and neurotensin (NT), was stud- ied on acutely extirpated rat dorsal root ganglia (DRGs) in vitro with intracellular recording techniques. Both normal and peripherally axotomized DRGs were analyzed, and recordings were made from C-type (small) and A-type (large) neurons. Galanin and sulfated cholecystokinin octapeptide, with one exception, had no effect on normal C- and A-type neurons but caused an inward current in both types of neurons after sciatic nerve cut. In normal rats, NT caused an outward current in C-type neurons and an inward current in A-type neurons. After sciatic nerve cut, NT only caused an inward current in both C- and A-type neurons.
机译：通过细胞内记录技术，在体外对急性切除的大鼠背根神经节（DRGs）研究了甘丙肽，硫酸化胆囊收缩素八肽和神经降压素（NT）这三种肽的作用。分析了正常的和外周切开的DRG，并记录了C型（小）和A型（大）神经元。甘丙肽和硫酸化胆囊收缩素八肽，除了一个例外，对正常的C型和A型神经元无影响，但在坐骨神经切开后对两种类型的神经元均产生内向电流。在正常大鼠中，NT在C型神经元中引起外向电流，而在A型神经元中引起内向电流。坐骨神经切断后，NT仅在C型和A型神经元中引起内向电流。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号