Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus

Peter L. Collins; Myron G. Hill; Juan Cristina

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Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus

机译：呼吸道合胞病毒（一种非分段的负链RNA病毒）的转录延伸因子

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摘要

RNA synthesis by the paramyxovirus respi- ratory syncytial virus, a ubiquitous human pathogen, was found to be more complex than previously appreciated for the nonsegmented negative-strand RNA viruses. Intracellular RNA replication of a plasmid-encoded "minigenome" analog of viral genomic RNA was directed by coexpression of the N, P, and L proteins. But, under these conditions, the greater part of mRNA synthesis terminated prematurely.

机译：发现副粘病毒呼吸道合胞病毒（一种普遍存在的人类病原体）的RNA合成比以前对无节段负链RNA病毒的认识更为复杂。病毒基因组RNA的质粒编码“微型基因组”类似物的细胞内RNA复制是通过N，P和L蛋白的共表达来指导的。但是，在这些条件下，mRNA合成的大部分会提前终止。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第1期|p.81-85|共5页
作者
Peter L. Collins; Myron G. Hill; Juan Cristina;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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2. Detection and quantitation of human respiratory syncytial virus (RSV) using minigenome cDNA and a Sindbis virus replicon: a prototype assay for negative-strand RNA viruses [J] . Olivo PD, Collins PL, Peeples ME, Virology . 1998,第1期

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3. Transcription and replication of nonsegmented negative-strand RNA viruses. [J] . Whelan SP, Barr JN, Wertz GW Current topics in microbiology and immunology . 2004,第0期

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机译：呼吸道合胞病毒感染肺泡上皮细胞系A549激活宿主细胞基因表达：氧化还原反应性转录因子NF-κB的作用。
6. Transcription elongation factor of respiratory syncytial virus a nonsegmented negative-strand RNA virus. [O] . P L Collins, M G Hill, J Cristina, 1996

机译：呼吸道合胞病毒（一种非分段的负链RNA病毒）的转录延伸因子。
7. Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus. [O] . Collins, P L, Hill, M G, Cristina, J, 1996

机译：呼吸道合胞病毒（一种非分段的负链RNA病毒）的转录延伸因子。
8. Interleukin-8 Expression in Normal Nasal Epithelium and Its Modulation byInfection with Respiratory Syncytial Virus and Cytokines Tumor Necrosis Factor, Interleukin-1, and Interleukin-6 [R] . Becker, S., Koren, H. S., Henke, D. C. 1993

机译：白细胞介素-8在正常鼻上皮细胞中的表达及其对呼吸道合胞病毒和细胞因子肿瘤坏死因子，白细胞介素-1和白细胞介素-6感染的调节作用

Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus

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