Viruses, cytokines, antigens, and autoimmunity

Roberto Gianani; Nora Sarvetnick

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Viruses, cytokines, antigens, and autoimmunity

【24h】

Viruses, cytokines, antigens, and autoimmunity

机译：病毒，细胞因子，抗原和自身免疫

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

To explain the pathogen- esis of autoimmunity, we hypothesize that following an infection the immune re- sponse spreads to tissue-specific autoan- tigens in genetically predisposed individ- uals eventually determining progression to disease. Molecular mimicry between viral and self antigens could, in some instances, initiate autoimmunity. Local elicitation of inflammatory cytokines fol- lowing infection probably plays a pivotal role in determining loss of functional tolerance to self autoantigens and the destructive activation of autoreactive cells.

机译：为了解释自身免疫的病原学，我们假设感染后免疫反应会扩散到遗传易感性个体中的组织特异性自身动物体内，最终决定疾病的进展。在某些情况下，病毒和自身抗原之间的分子模拟可以启动自身免疫。感染后炎症细胞因子的局部诱导可能在确定自身自身抗原的功能耐受性丧失和自身反应性细胞的破坏性激活中起关键作用。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第6期|p.2257-2259|共3页
作者
Roberto Gianani; Nora Sarvetnick;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Regulation of Cytokine-Driven Functional Differentiation of CD8 T Cells by Suppressor of Cytokine Signaling 1 Controls Autoimmunity and Preserves Their Proliferative Capacity toward Foreign Antigens [J] . Sheela Ramanathan, Stephanie Dubois, Julien Gagnon, The journal of immunology . 2010,第1期

机译：细胞因子信号1抑制剂抑制细胞因子驱动的CD8 T细胞功能分化控制自身免疫，并保留其对外源抗原的增殖能力。
2. Regulation of cytokine-driven functional differentiation of CD8 T cells by suppressor of cytokine signaling 1 controls autoimmunity and preserves their proliferative capacity toward foreign antigens. [J] . Ramanathan S, Dubois S, Gagnon J, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2010,第1期

机译：通过抑制细胞因子信号传导1来调节细胞因子驱动的CD8 T细胞功能分化，可控制自身免疫并保留其对外源抗原的增殖能力。
3. Antigen-nonspecific activation of CD8+ T lymphocytes by cytokines: relevance to immunity, autoimmunity, and cancer [J] . Sheela Ramanathan, Julien Gagnon, Subburaj Ilangumaran Archivum Immunologiae et Therapiae Experimentalis . 2008,第5期

机译：细胞因子对CD8 + T淋巴细胞的抗原非特异性激活：与免疫，自身免疫和癌症的相关性
4. Studies of effects on CD antigens expression and cytokines secretion of lymphocytes infected by human herpesvirus 6 and 7 in vitro [C] . Peng Guang-Yong, Yao Kun, Ren Qiang, 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：体外研究人疱疹病毒6和7感染淋巴细胞对CD抗原表达和细胞因子分泌的影响
5. The development of DNA vaccines containing genes expressing specific enterotoxigenic Escherichia coli antigens and cytokines for the enhancement of antibody production. [D] . Cho, Suk Hyeon. 2003

机译：DNA疫苗的开发，该疫苗含有表达特异性产肠毒素的大肠杆菌抗原和细胞因子的基因，以增强抗体的产生。
6. Viruses cytokines antigens and autoimmunity. [O] . R Gianani, N Sarvetnick 1996

机译：病毒细胞因子抗原和自身免疫。
7. Viruses, cytokines, antigens, and autoimmunity. [O] . Gianani, R, Sarvetnick, N 1996

机译：病毒，细胞因子，抗原和自身免疫。

Viruses, cytokines, antigens, and autoimmunity

摘要

著录项

相似文献

相关主题

期刊订阅