Protein-protein interaction: A genetic selection for compensating mutations at the barnase-barstar interface

Milan Jucovic; Robert W. Hartley

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Protein-protein interaction: A genetic selection for compensating mutations at the barnase-barstar interface

机译：蛋白质-蛋白质相互作用：补偿barnase-barstar界面突变的遗传选择

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Barnase and barstar are trivial names of the extracellular RNase and its intracellular inhibitor produced by Bacillus amyloliquefaciens. Inhibition involves the formation of a very tight one-to-one complex of the two proteins. With the crystallographic solution of the structure of the barnase- barstar complex and the development of methods for mea- suring the free energy of binding, the pair can be used to study protein-protein recognition in detail.

机译：Barnase和barstar是解淀粉芽孢杆菌产生的细胞外RNase及其细胞内抑制剂的简称。抑制涉及两种蛋白质非常紧密的一对一复合物的形成。随着barnase-barstar配合物结构的晶体学解决方案和测量结合自由能的方法的发展，该对可用于详细研究蛋白质-蛋白质识别。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第6期|p.2343-2347|共5页
作者
Milan Jucovic; Robert W. Hartley;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. ENERGETICS OF PROTEIN-PROTEIN INTERACTIONS - ANALYSIS OF THE BARNASE-BARSTAR INTERFACE BY SINGLE MUTATIONS AND DOUBLE MUTANT CYCLES [J] . Schreiber G., Fersht AR. Journal of Molecular Biology . 1995,第2期

机译：蛋白质相互作用的能量学-通过单突变和双突变周期分析巴纳斯-巴星接口
2. A positive genetic selection for disrupting protein-protein interactions: Identification of CREB mutations that prevent association with the coactivator CBP [J] . Hsiu-ming Shih, Phyllis S. Goldman, Anthony J. DeMaggio Proceedings of the National Academy of Sciences of the United States of America . 1996,第24期

机译：破坏蛋白质-蛋白质相互作用的积极遗传选择：鉴定可防止与共激活因子CBP缔合的CREB突变
3. Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles [J] . Jeffrey R. Brender, Yang Zhang PLoS Computational Biology . 2015,第10期

机译：通过基于结构的界面概况预测突变对蛋白质与蛋白质结合相互作用的影响
4. Extracting Protein-Protein Interactions Affected by Mutations via Auxiliary Task and Domain Pre-trained Model [C] . Yu Wang, Shaowu Zhang, Yijia Zhang, IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：通过辅助任务和域预先训练的模型提取受突变影响的蛋白质 - 蛋白质相互作用
5. Relation Extraction for Protein-Protein Interactions Affected by Mutations [D] . Fan, Ziling 2018

机译：突变影响的蛋白质-蛋白质相互作用的关系提取
6. Protein-protein interaction: a genetic selection for compensating mutations at the barnase-barstar interface. [O] . M Jucovic, R W Hartley 1996

机译：蛋白质-蛋白质相互作用：补偿barnase-barstar界面突变的遗传选择。
7. Protein-protein interaction: a genetic selection for compensating mutations at the barnase-barstar interface. [O] . Jucovic, M, Hartley, R W 1996

机译：蛋白质-蛋白质相互作用：补偿barnase-barstar界面突变的遗传选择。

Protein-protein interaction: A genetic selection for compensating mutations at the barnase-barstar interface

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