Cardioprotective effects of 70-kDa heat shock protein in transgenic mice

Nina B. Radford; Maggy Fina; Ivor J. Benjamin

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Cardioprotective effects of 70-kDa heat shock protein in transgenic mice

机译：70 kDa热休克蛋白对转基因小鼠的心脏保护作用

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Heat shock proteins are proposed to limit injury resulting from diverse environmental stresses, but direct metabolic evidence for such a cytoprotective function in vertebrates has been largely limited to studies of cultured cells. We generated lines of transgenic mice to express human 70-kDa heat shock protein constitutively in the myocardium.

机译：提出了热休克蛋白以限制由多种环境压力引起的损伤，但是在脊椎动物中这种细胞保护功能的直接代谢证据主要限于对培养细胞的研究。我们生成了转基因小鼠品系，以在心肌中组成型表达人类70 kDa热激蛋白。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第6期|p.2339-2342|共4页
作者
Nina B. Radford; Maggy Fina; Ivor J. Benjamin;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Induction of overexpression of the 27- and 70-kDa heat shock proteins by bicyclol attenuates concanavalin A-Induced liver injury through suppression of nuclear factor-kappaB in mice. [J] . Bao XQ, Liu GT Molecular pharmacology. . 2009,第5期

机译：双环醇诱导27 kDa和70 kDa热休克蛋白的过表达通过抑制小鼠中的核因子kappaB减弱了伴刀豆球蛋白A引起的肝损伤。
2. Effects of noopept and cortexin on the behavior of matured rats treated with corticoliberin or 70-kDa heat shock proteins in early ontogeny [J] . Shabanov PD, Lebedev AA, Stetsenko VP, Эκспериментальная и κлиничесκая фармаκология . 2007,第1期

机译：Noeptept和cortexin对皮质酮或70 kDa热激蛋白处理的成年大鼠早期行为的影响
3. Effects of noopept and cortexin on the behavior of matured rats treated with corticoliberin or 70-kDa heat shock proteins in early ontogeny [J] . Shabanov PD, Lebedev AA, Stetsenko VP, Эκспериментальная и κлиничесκая фармаκология . 2007,第1期

机译：nopept和cortexin对脑膜炎皮质醇或70-kda热休克蛋白治疗的成熟大鼠行为的影响
4. Enhancement of Th1 immune response by CDSalpha~+dendritic cells loaded with tumor extract enriched with heat shock proteins in tumor bearing mice [C] . Azadmehr Abbas, Pourfathollah Ali Akbar, Amirghofran Zahra, European Congress of Immunology . 2009

机译：Cdsalpha〜+树突状细胞的增强含有肿瘤萃取物的Cdsalpha〜+树突细胞的免疫应答富含热冲击蛋白在肿瘤轴承小鼠中
5. GENETICS AND FUNCTION IN TRANSGENIC MICE OF A CHIMERIC GENE DERIVED FROM DROSOPHILA MELANOGASTER HEAT SHOCK PROTEIN 70 AND HUMAN GROWTH HORMONE [D] . SOSNOWSKI, RONALD GEORGE 1987

机译：嗜黑果蝇热休克蛋白70和人类生长激素衍生的嵌合基因的转基因小鼠的遗传学和功能
6. Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. [O] . N B Radford, M Fina, I J Benjamin, 1996

机译：70 kDa热休克蛋白对转基因小鼠的心脏保护作用。
7. Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. [O] . Radford, N B, Fina, M, Benjamin, I J, 1996

机译：70 kDa热休克蛋白对转基因小鼠的心脏保护作用。

Cardioprotective effects of 70-kDa heat shock protein in transgenic mice

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