Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice

Sunghee Cho; Jin H. Son; Dong H. Park

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Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice

机译：转基因小鼠靶细胞神经递质表型改变后的交感神经减少

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Neurotransmitters play a variety of impor- tant roles during nervous system development. In the present study, we hypothesized that neurotransmitter phenotype of both projecting and target cells is an important factor for the final synaptic linkage and its specificity. To test this hypoth- esis, we used transgenic techniques to convert serotonin/ melatonin-producing cells of the pineal gland into cells that also produce dopamine and investigated the innervation of the phenotypically altered target cells.

机译：神经递质在神经系统发育过程中起着多种重要作用。在本研究中，我们假设投射细胞和靶细胞的神经递质表型是最终突触连接及其特异性的重要因素。为了验证这一假设，我们使用了转基因技术将松果体中产生5-羟色胺/褪黑激素的细胞转化为也产生多巴胺的细胞，并研究了表型改变的靶细胞的神经支配。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.2862-2866|共5页
作者
Sunghee Cho; Jin H. Son; Dong H. Park;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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2. Alteration of the natural killer repertoire in H-2 transgenic mice: specificity of rapid lymphoma cell clearance determined by the H-2 phenotype of the target. [J] . P H?glund, R Glas, C Ohlén, The Journal of Experomental Medicine . 1991,第2期

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5. The role of autocrine Wnt5a/Ror signalling in sympathetic target innervation. [D] . Ryu, Yun Kyoung. 2013

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6. Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice. [O] . S Cho, J H Son, D H Park, 1996

机译：转基因小鼠中靶细胞神经递质表型改变后的交感神经减少。
7. Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice. [O] . Cho, S, Son, J H, Park, D H, 1996

机译：转基因小鼠中靶细胞神经递质表型改变后的交感神经减少。

Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice

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