Thermal unfolding of human high-density apolipoprotein A-1: Implications for a lipid-free molten globular state

Olga Gursky; David Atkinson

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Thermal unfolding of human high-density apolipoprotein A-1: Implications for a lipid-free molten globular state

机译：人类高密度载脂蛋白A-1的热解：对无脂质的熔融球状状态的影响

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摘要

Apolipoprotein A-1 (apoA-1) in complex with high-density lipoprotein is critically involved in the transport and metabolism of cholesterol and in the pathogenesis of atherosclerosis. We reexamined the thermal unfolding of lipid- free apoA-1 in low-salt solution at pH ≈7, by using differential scanning calorimetry and circular dichroism.

机译：与高密度脂蛋白复合的载脂蛋白A-1（apoA-1）关键参与胆固醇的运输和代谢以及动脉粥样硬化的发病机理。通过使用差示扫描量热法和圆二色性，我们重新检查了低盐溶液中无脂apoA-1在pH≈7时的热解折叠。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.2991-2995|共5页
作者
Olga Gursky; David Atkinson;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Lipid-free apolipoprotein A-I and discoidal reconstituted high-density lipoproteins differentially inhibit glucose-induced oxidative stress in human macrophages. [J] . Tabet F, Lambert G, Cuesta Torres LF, Arteriosclerosis, thrombosis, and vascular biology . 2011,第5期

机译：无脂载脂蛋白A-I和盘状重构高密度脂蛋白差异性抑制人巨噬细胞中葡萄糖诱导的氧化应激。
2. Evidence for the presence of lipid-free monomolecular apolipoprotein a-1 in plasma [J] . MiyazakiO., OgiharaJ., FukamachiI., Journal of Lipid Research . 2014,第2期

机译：血浆中存在无脂质单分子载脂蛋白a-1的证据
3. Evidence for the presence of lipid-free monomolecular apolipoprotein A-1 in plasma [J] . Osamu Miyazaki, Jun Ogihara, Isamu Fukamachi, Journal of Lipid Research . 2014,第2期

机译：血浆中存在无脂单分子载脂蛋白A-1的证据
4. Thermal unfolding of the manganese stabilizing 33 kD protein Photosystem II: implications for a molten globular state [C] . Lin-Fang Du, Hong Liu, Hou-Guo Liang International Congress on Photosynthesis . 2001

机译：锰稳定33 kd蛋白光系统II的热展开：对熔融球状州的影响
5. Unfolded, misfolded, and self-organized short alanine-rich peptides: Implications for fundamental science, human disease, and biotechnology. [D] . Measey, Thomas J. 2010

机译：折叠，折叠和自组织的富含丙氨酸的短肽：对基础科学，人类疾病和生物技术的意义。
6. Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state. [O] . O Gursky, D Atkinson 1996

机译：人类高密度载脂蛋白A-1的热解：对无脂质的熔融球状状态的影响。
7. Thermal unfolding of human high-density apolipoprotein A-1: implications for a lipid-free molten globular state. [O] . Gursky, O, Atkinson, D 1996

机译：人类高密度载脂蛋白A-1的热解：对无脂质的熔融球状状态的影响。

Thermal unfolding of human high-density apolipoprotein A-1: Implications for a lipid-free molten globular state

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