Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions

Jasmina N. Jovanovic; Fabio Benfenati; Yaw L. Siow

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Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions

机译：神经营养蛋白通过MAP激酶刺激突触素I磷酸化并调节突触素I-肌动蛋白相互作用

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The ability of neurotrophins to modulate the survival and differentiation of neuronal populations involves the Trk/MAP (mitogen-activated protein kinase) kinase sig- naling pathway. More recently, neurotrophins have also been shown to regulate synaptic transmission. The synapsins are a family of neuron-specific phosphoproteins that play a role in regulation of neurotransmitter release, in axonal elongation, and in formation and maintenance of synaptic contacts.

机译：神经营养蛋白调节神经元种群存活和分化的能力涉及Trk / MAP（促分裂原活化蛋白激酶）激酶的信号通路。最近，神经营养蛋白也显示出调节突触传递的作用。突触蛋白是神经元特异性磷蛋白的家族，其在调节神经递质释放，轴突伸长以及突触接触的形成和维持中起作用。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第8期|p.3679-3683|共5页
作者
Jasmina N. Jovanovic; Fabio Benfenati; Yaw L. Siow;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Leucine‐rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre‐synaptic sites [J] . Marte Antonella, Russo Isabella, Rebosio Claudia, Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2019,第3期

机译：富含亮氨酸的重复激酶2 Synapsin的磷酸化I调节在突触前位点的谷氨酸释放
2. Integrin-Linked Kinase Is Involved in Cocaine Sensitization by Regulating PSD-95 and Synapsin I Expression and GluR1 Ser845 Phosphorylation [J] . Qiang Chen, Xiongzhao Zhu, Yu Zhang, Journal of Molecular Neuroscience . 2010,第3期

机译：整合素连接激酶通过调节PSD-95和突触蛋白I的表达以及GluR1 Ser845的磷酸化参与可卡因的致敏
3. Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. [J] . Chen Q, Zhu X, Zhang Journal of Molecular Neuroscience: MN . 2010,第3期

机译：整联蛋白连接的激酶通过调节PSD-95和突触蛋白I的表达以及GluR1 Ser845磷酸化而参与可卡因致敏。
4. Camk Ⅱ Can Be Activated by Ginsenoside Rb1 But Not Involved In Rb1 Enhanced Synapsin Phosphorylation and Glutamate Releasea [C] . Enrique Cortes-Diaz, rnAngel Ramon-Garay, rnFernando Tellez-Hernández, Proceedin of 2008 International Conference on Ginseng . 2008

机译：人参皂苷Rb1可以激活CamkⅡ，但不参与Rb1增强的突触素磷酸化和谷氨酸释放。
5. MAP kinases phosphorylate SPF45 and regulate its alternative splicing function: Insights onto phosphorylation-dependent and -independent effects in ovarian cancer cells. [D] . Al-Ayoubi, Adnan. 2012

机译：MAP激酶使SPF45磷酸化并调节其选择性剪接功能：洞悉卵巢癌细胞中磷酸化依赖性和非依赖性作用。
6. Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. [O] . J N Jovanovic, F Benfenati, Y L Siow, 1996

机译：神经营养蛋白通过MAP激酶刺激突触素I的磷酸化并调节突触素I-肌动蛋白的相互作用。
7. Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. [O] . Jovanovic, J N, Benfenati, F, Siow, Y L, 1996

机译：神经营养蛋白通过MAP激酶刺激突触素I的磷酸化并调节突触素I-肌动蛋白的相互作用。

Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions

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