Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: A novel ATP-binding cassette transporter

Marcel A. van Kuijck; Remon A. M. H. van Aubel; Andreas E. Busch

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: A novel ATP-binding cassette transporter

【24h】

Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: A novel ATP-binding cassette transporter

机译：环状AMP激活的氯化物电导调节剂的分子克隆和表达：一种新型的ATP结合盒转运蛋白。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-regulated, cAMP-activated chloride channel located in the apical membrane of many epithelial secretory cells. Here we report cloning of a cAMP-activated epithelial basolateral chloride conductance regulator (EBCR) that appears to be a basolateral CFTR counterpart. This novel chloride channel or regulator shows 49/100 identity with multidrug resistance-associated protein (MRP) and 29/100 identity with CFTR.

机译：囊性纤维化跨膜电导调节剂（CFTR）是ATP调节的cAMP活化的氯离子通道，位于许多上皮分泌细胞的顶膜中。在这里，我们报告的cAMP激活的上皮基底外侧氯化物电导调节剂（EBCR）的克隆似乎是基底外侧CFTR的对应物。这种新型的氯离子通道或调节剂与多重耐药相关蛋白（MRP）表现出49/100的身份，与CFTR表现出29/100的身份。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第11期|p.5401-5406|共6页
作者
Marcel A. van Kuijck; Remon A. M. H. van Aubel; Andreas E. Busch;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Molecular cloning and expression profile of an ATP-binding cassette (ABC) transporter gene from the hemipteran insect Nilaparvata lugens [J] . W.J. Zha, S.H. Li, L. Zhou, Genetics and Molecular Research . 2015,第1期

机译：半翅目昆虫Nilaparvata lugens ATP结合盒（ABC）转运蛋白基因的分子克隆和表达谱
2. Demonstration of Phosphoryl Group Transfer Indicates That the ATP-binding Cassette (ABC) Transporter Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Exhibits Adenylate Kinase Activity [J] . Christoph O. Randak, Amanda R. Ver Heul, Michael Welsh The Journal of biological chemistry . 2012,第43期

机译：磷酰基转移的证明表明ATP结合盒（ABC）转运囊性纤维化跨膜电导调节剂（CFTR）表现出腺苷酸激酶活性
3. A Unified View of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gating: Combining the Allosterism of a Ligand-gated Channel with the Enzymatic Activity of an ATP-binding Cassette (ABC) Transporter [J] . Kevin L. Kirk, Wei Wang The Journal of biological chemistry . 2011,第15期

机译：囊性纤维化跨膜电导调节剂（CFTR）门控的统一视图：将配体门控通道的变色剂与ATP结合盒（ABC）转运蛋白的酶活性相结合
4. ON-CHIP SINGLE VESICLE ANALYSES OF ATP-BINDING CASSETTE (ABC) TRANSPORTERS [C] . H. Sasaki, R. Kawano, T. Osaki, International Conference on Miniaturized Systems for Chemistry and Life Sciences . 2011

机译：ATP结合盒（ABC）转运蛋白的片上单囊泡分析
5. Effect of metabolic disease and xenobiotic exposure on hepatic ATP-binding cassette (Abc) drug transporter expression. [D] . Donepudi, Ajay Chowdary. 2013

机译：代谢疾病和异源生物暴露对肝ATP结合盒（Abc）药物转运蛋白表达的影响。
6. Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: a novel ATP-binding cassette transporter. [O] . M A van Kuijck, R A van Aubel, A E Busch, 1996

机译：环状AMP激活的氯化物电导调节剂的分子克隆和表达：一种新型的ATP结合盒转运蛋白。
7. Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: a novel ATP-binding cassette transporter. [O] . van Kuijck, M A, van Aubel, R A, Busch, A E, 1996

机译：环状AMP激活的氯化物电导调节剂的分子克隆和表达：一种新型的ATP结合盒转运蛋白。

Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: A novel ATP-binding cassette transporter

摘要

著录项

相似文献

相关主题

期刊订阅