Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation

David F. Steele; Christine A. Butler; Thomas D. Fox

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation

【24h】

Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation

机译：插入到酵母线粒体DNA中的已编码核基因的表达受到mRNA特异性翻译激活的限制

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Genetic code differences prevent expression of nuclear genes within Saccharomyces cerevisiae mitochon- dria. To bridge this gap a synthetic gene, ARG8m, designed to specify an arginine biosynthetic enzyme when expressed in- side mitochondria, has been inserted into yeast mtDNA in place of the COX3 structural gene. This mitochondrial cox3::ARG8m gene fully complements a nuclear arg8 deletion at the level of cell growth, and it is dependent for expression upon nuclear genes that encode subunits of the COX3 mRNA- specific translational activator.

机译：遗传密码的不同会阻止酿酒酵母线粒体内核基因的表达。为了弥合这一差距，已将一种设计用于在线粒体内表达时指定一种精氨酸生物合成酶的合成基因ARG8m插入酵母mtDNA中，以代替COX3结构基因。线粒体cox3 :: ARG8m基因在细胞生长水平上完全补充了核arg8缺失，并且其表达依赖于编码COX3 mRNA特异性翻译激活子亚基的核基因的表达。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第11期|p.5253-5257|共5页
作者
David F. Steele; Christine A. Butler; Thomas D. Fox;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Highly Diverged Homologs of Saccharomyces cerevisiae Mitochondrial mRNA-Specific Translational Activators Have Orthologous Functions in Other Budding Yeasts [J] . Elizabeth H. Williams, G. Desmond Clark-Walker, Maria C. Costanzo, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2000,第3期

机译：酿酒酵母线粒体mRNA特定翻译激活剂的高度同源同源物在其他芽酵母中具有直系同源功能。
2. Functional interactions among two yeast mitochondrial ribosomal proteins and an mRNA-specific translational activator. [J] . P Haffter, T D Fox, T W McMullin Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1991,第2期

机译：两种酵母线粒体核糖体蛋白与mRNA特异性翻译激活剂之间的功能相互作用。
3. A genetic link between an mRNA-specific translational activator and the translation system in yeast mitochondria. [J] . P Haffter, T D Fox, T W McMullin Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1990,第3期

机译：mRNA特异性翻译激活剂与酵母线粒体翻译系统之间的遗传联系。
4. Limited Genetic Diversity of Chinese Muscovy Duck (Cairina moschata) Revealed by Partial Sequences of Mitochondrial DNA Cytochrome b Gene [C] . Jing Sun, Jing Huang, Xiaoling Zhao, Information technology and agricultural engineering . 2011

机译：线粒体DNA细胞色素b基因部分序列揭示的番鸭遗传多样性有限
5. Biochemical and genetic characterization of mitochondrial encephalomyopathies resulting from mitochondrial-DNA (mtDNA) and nuclear DNA (nDNA) mutations. [D] . Zheng, Xianxian. 1990

机译：由线粒体DNA（mtDNA）和核DNA（nDNA）突变引起的线粒体脑肌病的生化和遗传特征。
6. Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation. [O] . D F Steele, C A Butler, T D Fox 1996

机译：插入到酵母线粒体DNA中的已编码核基因的表达受到mRNA特异性翻译激活的限制。
7. Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation. [O] . Steele, D F, Butler, C A, Fox, T D 1996

机译：插入到酵母线粒体DNA中的已编码核基因的表达受到mRNA特异性翻译激活的限制。

Expression of a recoded nuclear gene inserted into yeast mitochondrial DNA is limited by mRNA-specific translational activation

摘要

著录项

相似文献

相关主题

期刊订阅