Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage

Sheldon Wolff; Veena Afzal

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Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage

机译：将DNA多核苷酸链分离成姐妹染色单体，并使用内复制的细胞追踪由交联，烷基化或X射线损伤诱导的姐妹染色单体交换

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The method of Matsumoto and Ohta [Mat- sumoto, K. & Ohta, T. (1992) Chromosoma 102, 60-65; Matsumoto, K. & Ohta, T. (1995) Mutat. Res. 326, 93-98] to induce large numbers of endoreduplicated Chinese hamster ovary cells has now been coupled with the fluorescence-plus- Giemsa method of Perry and Wolff [Perry, P. & Wolff, S. (1974) Nature (London) 251, 156-158] to produce harlequin endoreduplicated chromosomes that after the third round of DNA replication are composed of a chromosome with a light chromatid and a dark chromatid in close apposition to its sister chromosome containing two light chromatids.

机译：Matsumoto和Ohta的方法[Mat-sumoto，K。＆Ohta，T。（1992），Chromosoma 102，60-65； J.Am.Chem.Soc。，1992，10：1877-63]。 Matsumoto，K。＆Ohta，T。（1995）Mutat。 Res。 [326，93-98]诱导大量内复制的中国仓鼠卵巢细胞现已与Perry和Wolff的荧光加Giemsa方法结合[Perry，P.＆Wolff，S.（1974）Nature（London）251 ，156-158]产生丑角内复制的染色体，该染色体在第三轮DNA复制后，由一个带有亮染色单体和一个暗染色单体的染色体组成，该染色体与包含两个亮染色单体的姊妹染色体紧靠。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第12期|p.5765-5769|共5页
作者
Sheldon Wolff; Veena Afzal;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. Induction of DNA strand breaks, DNA-protein crosslinks and sister chromatid exchanges by arsenite in a human lung cell line. [J] . Mouron SA, Grillo CA, Dulout FN, Toxicology in vitro: an international journal published in association with BIBRA . 2006,第3期

机译：亚砷酸盐在人肺细胞系中诱导DNA链断裂，DNA-蛋白质交联和姐妹染色单体交换。
2. A comparative investigation of DNA strand breaks, sister chromatid exchanges and K-ras gene mutations induced by cadmium salts in cultured human cells. [J] . Mouron SA, Grillo CA, Dulout FN, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2004,第2期

机译：镉盐在培养的人细胞中诱导的DNA链断裂，姐妹染色单体交换和K-ras基因突变的比较研究。
3. Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells. [J] . Dodson Helen, Morrison Ciaran G. Nucleic Acids Research . 2009,第18期

机译：姐妹染色单体的内聚力增加和DNA损伤反应因子在脊椎动物细胞中被酶诱导的DNA双链断裂处定位。
4. Evaluation of radioprotection properties of propolis by chromosomal alterations, cell proliferation kinetics, mitotic index and sister chromatid exchange. [C] . Alegria Montoro, Joan Francesc Barquinero, Miguel Almonacid, Congress of the International Radiation Protection Association;IRPA 12 . 2010

机译：通过染色体改变，细胞增殖动力学，有丝分裂指数和姐妹染色单体交换评估蜂胶的辐射防护特性。
5. FREQUENCY OF SISTER CHROMATID EXCHANGES AND CELL CYCLE KINETICS IN CULTURED HUMAN LYMPHOCYTES TREATED WITH SELENIUM ALONE OR SELENIUM AND METHYLNITROSOUREA. [D] . KHALIL, AHMAD MOHAMMAD. 1987

机译：硒单独或硒和亚甲基亚硝基脲处理的人淋巴细胞中的染色体染色交换和细胞周期动力学的频率。
6. Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks alkylations or x-ray damage. [O] . S Wolff, V Afzal 1996

机译：将DNA多核苷酸链分离成姐妹染色单体并使用内复制的细胞追踪由交联烷基化或X射线损伤诱导的姐妹染色单体交换。
7. Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage. [O] . Wolff, S, Afzal, V 1996

机译：将DNA多核苷酸链分离成姐妹染色单体，并使用核内复制的细胞追踪由交联，烷基化或X射线损伤诱导的姐妹染色单体交换。

Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage

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