Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs

Koyomi Miyazaki; Kohji Uchiyama; Yutaka Imokawa

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Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs

机译：再生new肢体基质金属蛋白酶cDNA的克隆与鉴定

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Matrix metalloproteinases (MMPs) of re- generating urodele limbs have been suggested to play crucial roles in the process of the dedifferentiation of cells in the damaged tissues and the ensuing blastema formation because the activation of MMPs is an early and conspicuous event occurring in the amputated limb. MMP cDNAs were cloned as products of the reverse transcription-PCR from cDNA library- ies of newt limbs, and their structures were characterized.

机译：有人建议，再生的urodele肢体的基质金属蛋白酶（MMPs）在受损组织中的细胞去分化和随后的胚层形成过程中起关键作用，因为MMPs的激活是截肢中发生的早期且明显的事件。肢。从new肢的cDNA文库中克隆了作为逆转录PCR产物的MMP cDNA，并对其结构进行了表征。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第13期|p.6819-6824|共6页
作者
Koyomi Miyazaki; Kohji Uchiyama; Yutaka Imokawa;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration. [J] . Stevenson TJ, Vinarsky V, Atkinson DL, Developmental dynamics: an official publication of the American Association of Anatomists . 2006,第3期

机译：金属蛋白酶1的组织抑制剂在s肢再生过程中调节基质金属蛋白酶活性。
2. Characterization of a newt tenascin cDNA and localization of tenascin mRNA during newt limb regeneration by in situ hybridization☆ [J] . Hiroaki Onda, Matthew L. Poulin, Roy A. Tassava, Developmental biology . 1991,第1期

机译：原位杂交技术在a肢腱再生过程中鉴定ten肌腱蛋白cDNA和腱生蛋白mRNA的定位☆
3. Normal newt limb regeneration requires matrix metalloproteinase function [J] . Vinarsky V, Atkinson DL, Stevenson TJ, Developmental biology . 2005,第1期

机译：正常的limb肢再生需要基质金属蛋白酶功能
4. Newt limb regeneration studied with synchrotron microCT [C] . S.R. Stock, K.I. Ignatiev, H.G. Simon, Developments in X-Ray Tomography IV . 2004

机译：用同步加速器microCT研究的肢体再生
5. Cloning and characterization of newt tenascincDNA: Its expression in regenerating limbs and healing wounds of newts and Xenopus [D] . Onda, Hiroaki 1993

机译：ten肌腱蛋白cDNA的克隆和表征：其在ts和爪蟾再生肢体和伤口愈合中的表达
6. Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs. [O] . K Miyazaki, K Uchiyama, Y Imokawa, 1996

机译：再生new肢基质金属蛋白酶cDNA的克隆与鉴定。
7. Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs. [O] . Miyazaki, K, Uchiyama, K, Imokawa, Y, 1996

机译：再生new肢基质金属蛋白酶cDNA的克隆与鉴定。
8. Extracellular Matrix Regulations of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) and Matrix Metalloproteinase-2 (MMP-2) in Human Breast Fibroblasts. [R] . Hernandez-Barrantes, S., Fridman, R. 2002

机译：人乳腺成纤维细胞膜型1基质金属蛋白酶（mT1-mmp）和基质金属蛋白酶-2（mmp-2）的细胞外基质调节。

Cloning and characterization of cDNAs for matrix metalloproteinases of regenerating newt limbs

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