Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain

Frederic P. Lemaigre; Serge M. Durviaux; Oanh Truong

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Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain

机译：肝细胞核因子6，一种转录因子，包含新型同型结构域和单切结构域

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摘要

Tissue-specific transcription is regulated in part by cell type-restricted proteins that bind to defined sequences in target genes. The DNA-binding domain of these proteins is often evolutionarily conserved. On this basis, liver-enriched transcription factors were classified into five families. We describe here the mammalian prototype of a sixth family, which we therefore call hepatocyte nuclear factor 6 (HNF-6).

机译：组织特异性转录部分受与靶基因中定义序列结合的细胞类型限制蛋白的调控。这些蛋白质的DNA结合结构域通常在进化上是保守的。在此基础上，肝脏富集的转录因子被分为五个家族。我们在这里描述了第六家族的哺乳动物原型，因此我们将其称为肝细胞核因子6（HNF-6）。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第18期|p.9460-9464|共5页
作者
Frederic P. Lemaigre; Serge M. Durviaux; Oanh Truong;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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3. Hepatocyte nuclear factor 4 alpha ligand binding and F domains mediate interaction and transcriptional synergy with the pancreatic islet LIM HD transcription factor Isl1 [J] . Eeckhoute J, Briche I, Kurowska M, Journal of Molecular Biology . 2006,第4期

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机译：磷脂酰 - 肌醇3-激酶和GRB2SH2 / SH3结构肝细胞生长因子/散射因子诱导的生长，运动和侵袭的差异要求
5. Functional characterization and regulation of liver transcription factors hepatocyte nuclear factor 3. [D] . Qian, Xiaobing. 1994

机译：肝转录因子肝细胞核因子的功能表征和调节3。
6. Hepatocyte nuclear factor 6 a transcription factor that contains a novel type of homeodomain and a single cut domain. [O] . F P Lemaigre, S M Durviaux, O Truong, 1996

机译：肝细胞核因子6一种转录因子包含一种新型的同源域和一个单切域。
7. Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain. [O] . Lemaigre, F P, Durviaux, S M, Truong, O, 1996

机译：肝细胞核因子6，一种转录因子，包含一种新型的同源域和一个单切域。

Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain

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