P2Y_1 purinergic receptors in sensory neurons: Contribution to touch-induced impulse generation

Fumio Nakamura; Stephen M. Strittmatter

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P2Y_1 purinergic receptors in sensory neurons: Contribution to touch-induced impulse generation

机译：感觉神经元中的P2Y_1嘌呤能受体：对触摸感应脉冲产生的贡献

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Somatic sensation requires the conversion of physical stimuli into the depolarization of distal nerve end- ings. A single cRNA derived from sensory neurons renders Xenopus laevis oocytes mechanosensitive and is found to en- code a P2Y_1 purinergic receptor. P2Y_1 mRNA is concentrated in large-fiber dorsal root ganglion neurons. In contrast, P2X_3 mRNA is localized to small-fiber sensory neurons and pro- duces less mechanosensitivity in oocytes.

机译：躯体感觉需要将物理刺激转换为远端神经末梢的去极化。源自感觉神经元的单个cRNA使非洲爪蟾卵母细胞具有机械敏感性，并被发现编码P2Y_1嘌呤能受体。 P2Y_1 mRNA集中在大纤维背根神经节神经元中。相反，P2X_3 mRNA定位于小纤维感觉神经元，并在卵母细胞中产生较小的机械敏感性。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第19期|p.10465-10470|共6页
作者
Fumio Nakamura; Stephen M. Strittmatter;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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6. P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation. [O] . F Nakamura, S M Strittmatter 1996

机译：感觉神经元中的P2Y1嘌呤能受体：对触摸感应脉冲产生的贡献。
7. P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation. [O] . Nakamura, F, Strittmatter, S M 1996

机译：感觉神经元中的P2Y1嘌呤能受体：对触摸感应脉冲产生的贡献。

P2Y_1 purinergic receptors in sensory neurons: Contribution to touch-induced impulse generation

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