Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G_1 phase

M. Knehr; M. Poppe; D. Schroeter

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Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G_1 phase

机译：人类着丝粒蛋白C的细胞表达表明在G_1期具有最高丰度的循环行为

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Centromere proteins are localized within the centromere-kinetochore complex, which can be proven by means of immunofluorescence microscopy and immunoelec- tron microscopy. In consequence, their putative functions seem to be related exclusively to mitosis, namely to the interaction of the chromosomal kinetochores with spindle microtubules. However, electron microscopy using immune sera enriched with specific antibodies against human centro- mere protein C (CENP-C) showed that it occurs not only in mitosis but during the whole cell cycle.

机译：着丝粒蛋白位于着丝粒-线粒体复合体内，这可以通过免疫荧光显微镜和免疫电子显微镜来证明。结果，它们的推定功能似乎仅与有丝分裂有关，即与染色体动植物与纺锤体微管的相互作用有关。然而，使用富含抗人类中心蛋白C（CENP-C）特异性抗体的免疫血清的电子显微镜显示，它不仅发生在有丝分裂中，而且发生在整个细胞周期中。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第19期|p.10234-10239|共6页
作者
M. Knehr; M. Poppe; D. Schroeter;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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机译：H3.3在S期的着丝粒处沉积，作为G_1期新组装的CENP-A的占位符
2. IGF-I stimulates human intestinal smooth muscle cell growth by regulation of G_1 phase cell cycle proteins [J] . John F. Kuemmerle, Huiping Zhou, Jennifer G. Bowers American Journal of Physiology . 2004,第3aPta1期

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3. Human Mcm proteins at a replication origin during the G_1 to S phase transition [J] . Daniel Schaarschmidt, Eva-Maria Ladenburger, Christian Keller, Nucleic Acids Research . 2002,第19期

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5. Investigations of cellular stress-responsive proteins and PGF gene expression in human trophoblast. [D] . Leavenworth, Jonathan Dean. 2009

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6. Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G1 phase. [O] . M Knehr, M Poppe, D Schroeter, 1996

机译：人着丝粒蛋白C的细胞表达表明在G1期具有最高丰度的循环行为。
7. Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G1 phase. [O] . Knehr, M, Poppe, M, Schroeter, D, 1996

机译：人着丝粒蛋白C的细胞表达表明在G1期具有最高丰度的循环行为。

Cellular expression of human centromere protein C demonstrates a cyclic behavior with highest abundance in the G_1 phase

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