A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters

Noam Shani; David Valle

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A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters

机译：人肾上腺白质营养不良转运蛋白的酿酒酵母同源物是两个半ATP结合盒式转运蛋白的异二聚体。

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摘要

The adrenoleukodystrophy protein (ALDP) and the 70-kDa peroxisomal membrane protein (PMP70) are half ATP-binding cassette (ABC) transporters in the human peroxisome membrane. ALDP and PMP70 share sequence homology and both are implicated in genetic diseases. PXA1 and YKL741 are Saccharomyces cerevisiae genes that encode homologs of ALDP and PMP70.

机译：肾上腺白质营养不良蛋白（ALDP）和70 kDa过氧化物酶体膜蛋白（PMP70）是人过氧化物酶体膜中的一半ATP结合盒（ABC）转运蛋白。 ALDP和PMP70具有序列同源性，都与遗传疾病有关。 PXA1和YKL741是啤酒酵母基因，其编码ALDP和PMP70的同源物。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第21期|p.11901-11906|共6页
作者
Noam Shani; David Valle;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Drug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5 [J] . KeniyaM.V., HolmesA.R., NiimiM., Molecular pharmaceutics . 2014,第10期

机译：通过表达全长黑素瘤相关的人类ATP结合盒转运蛋白ABCB5，赋予了模型酵母酿酒酵母以耐药性
2. Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 protein degradation. [J] . Xu Wang, Rongxin Deng, Yan Lu, Basic & clinical pharmacology & toxicology. . 2013,第1期

机译：藤黄酸作为ATP结合盒转运蛋白B1的非竞争性抑制剂，可通过促进ATP结合盒转运蛋白B1蛋白的降解来逆转人类上皮癌的多药耐药性。
3. Generating Symmetry in the Asymmetric ATP-binding Cassette (ABC) Transporter Pdr5 from Saccharomyces cerevisiae [J] . Rakeshkumar P. Gupta, Petra Kueppers, Nils Hanekop, The Journal of biological chemistry . 2014,第22期

机译：从糖酵母酿酒酵母中产生非对称ATP结合盒（ABC）转运蛋白的对称性
4. ON-CHIP SINGLE VESICLE ANALYSES OF ATP-BINDING CASSETTE (ABC) TRANSPORTERS [C] . H. Sasaki, R. Kawano, T. Osaki, International Conference on Miniaturized Systems for Chemistry and Life Sciences . 2011

机译：ATP结合盒（ABC）转运蛋白的片上单囊泡分析
5. The Drosophila ATP-Binding Cassette transporter gene dMRP is related to the human Multidrug Resistance-associated Protein (MRP) family and functions as a xenobiotic transporter. [D] . Cogbill, Jolene Noelani Tarnay. 2008

机译：果蝇ATP结合盒式转运蛋白基因dMRP与人类多药耐药相关蛋白（MRP）家族有关，并作为外源生物转运蛋白。
6. A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. [O] . N Shani, D Valle 1996

机译：人肾上腺白质营养不良转运蛋白的酿酒酵母同源物是两个半ATP结合盒转运蛋白的异二聚体。
7. A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. [O] . Shani, N, Valle, D 1996

机译：人肾上腺白质营养不良转运蛋白的酿酒酵母同源物是两个半ATP结合盒转运蛋白的异二聚体。

A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters

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