Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase

Ingrid Emerit; Frederic Garban; Jany Vassy

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Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase

机译：外源超氧化物歧化酶的超氧化物介导的裂发生和抗成胶作用

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Superoxide-mediated clastogenesis is char- acteristic for various chronic inflammatory diseases with autoimmune reactions and probably plays a role in radiation- induced clastogenesis and in the congenital breakage syn- dromes. It is consistently prevented by exogenous superoxide dismutase (SOD), but not by heat-inactivated SOD, indicating that the anticlastogenic effect is related to the catalytic function of the enzyme.

机译：超氧化物介导的裂发生具有多种具有自身免疫反应的慢性炎症性疾病的特征，并且可能在放射诱导的裂发生和先天性骨折综合征中起作用。始终通过外源超氧化物歧化酶（SOD）来防止这种情况，但是通过热灭活的SOD却不能阻止它的发生，这表明抗成弹性的作用与酶的催化功能有关。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第23期|p.12799-12804|共6页
作者
Ingrid Emerit; Frederic Garban; Jany Vassy;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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2. Low NO bioavailability in CCl₄cirrhotic rat livers might result from low NO synthesis combined with decreased superoxide dismutase activity allowing superoxide-mediated NO breakdown: A comparison of two portal hypertensive rat models with heal [J] . Marc Van de Casteele, Jos F van Pelt, Frederik Nevens, Comparative Hepatology . 2003,第4期

机译：CCl _{4 肝硬化大鼠肝脏中NO的生物利用度低可能是由于NO合成减少以及超氧化物歧化酶活性降低，从而使超氧化物介导的NO分解所致：比较两种具有门脉高压的门脉高压大鼠模型}
3. Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts [J] . Huang TT, Yasunami M, Carlson EJ, Archives of Biochemistry and Biophysics . 1997,第2期

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4. Over-expression of exogenous superoxide dismutase gene (MnSOD) and its effect on stress resistance in maize [C] . LI WANCHEN, Du JUAN Workshop of the International Maize and Wheat Improvement Center . 2004

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5. Modulation of manganese superoxide dismutase (MnSOD): Effects on proinflammatory and p53 signaling [D] . Robbins, Delira Freddi. 2012

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6. Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase [O] . Ingrid Emerit, Frédéric Garban, Jany Vassy, 1996

机译：超氧化物介导的裂发生和抗成胶作用外源超氧化物歧化酶
7. On the Origin of Superoxide Dismutase: An Evolutionary Perspective of Superoxide-Mediated Redox Signaling [O] . Adam J. Case 2017

机译：超氧化物歧化酶的起源：超氧化物介导的氧化还原信号的进化观点

Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase

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