Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission

Pier Vincenzo Piazza; Michel Barrot; Franeoise Roug

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Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission

机译：抑制糖皮质激素分泌和抗精神病药对中脑边缘多巴胺能传递有相似的作用

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Specific antagonists of central dopaminergic receptors constitute the major class of antipsychotic drugs (APD). Two principal effects of APD are used as criteria for the pre-clinical screening of their antipsychotic action: (i) inhibition of basal and depolarization-induced activity of mesolimbic dopaminergic neurons; (ii) antagonism of the locomotor effects of dopaminergic agonists.

机译：中枢多巴胺能受体的特异性拮抗剂构成抗精神病药（APD）的主要类别。 APD的两个主要作用用作临床前筛查其抗精神病作用的标准：（i）抑制中脑边缘多巴胺能神经元的基础和去极化诱导的活性；（ii）多巴胺能激动剂的运动作用的拮抗作用。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第26期|p.15445-15450|共6页
作者
Pier Vincenzo Piazza; Michel Barrot; Franeoise Roug;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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2. Suppression of glucocorticoid secretion enhances cholinergic transmission in rat hippocampus. [J] . Mizoguchi K, Shoji H, Ikeda R, Brain research bulletin . 2008,第6期

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4. Different inhibitory effects by dopaminergic modulation and global suppression of activity [C] . Takuji Hayashi, Osamu Araki, Tohru Ikeguchi International Conference on Neural Networks . 2003

机译：多巴胺能调节和全局抑制活性的不同抑制作用
5. Behavioral and neurochemical effects of 5HT-related drugs in a model of mesolimbic dopamine hyperactivity [D] . Waddock, Sarah Louise 1997

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6. Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission [O] . Pier Vincenzo Piazza, Michel Barrot, Françoise Rougé-Pont, 1996

机译：抑制糖皮质激素分泌和抗精神病药对中脑边缘多巴胺能传输有类似的影响
7. 3,4-dihydroxyphenylacetic acid (DOPAC) and the rat mesolimbic dopaminergic pathway: drug effects and evidence for somatodendritic mechanisms. [O] . Beart, P. M., Gundlach, A. L. 1980

机译：3，4-二羟基苯乙酸（DOPAC）和大鼠中脑边缘多巴胺能途径：药物作用和体细胞树突机制的证据。
8. Mesolimbic and Nigrostriatal Dopaminergic Systems: Behavioral Neuropharmacology [R] . Hartgraves, S. L. 1985

机译：mesolimbic和Nigrostriatal Dopaminergic systems：Behavioral Neuropharmacology

Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission

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