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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Honesty mediates the relationship between serotonin and reaction to unfairness
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Honesty mediates the relationship between serotonin and reaction to unfairness

机译:诚实介导5-羟色胺与对不公平反应之间的关系

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摘要

How does one deal with unfair behaviors? This subject has long been investigated by various disciplines including philosophy, psychology,economics, and biology. However, our reactions to unfairness differ from one individual to another. Experimental economics studies using the ultimatum game (UG), in which players must decide whether to accept or reject fair or unfair offers, have also shown that there are substantial individual differences in reaction to unfairness. However,little is known about psychological as well as neurobiological mechanisms of this observation. We combined a molecular imaging technique, an economics game, and a personality inventory to elucidate the neurobiological mechanism of heterogeneous reactions to unfairness. Contrary to the common belief that aggressive personalities (impulsivity or hostility) are related to the high rejection rate of unfair offers in UG, we found that individuals with apparently peaceful personalities (straightforwardness and trust) rejected more often and were engaged in personally costly forms of retaliation. Furthermore, individuals with a low level of serotonin transporters in the dorsal raphe nucleus (DRN) are honest and trustful,and thus cannot tolerate unfairness, being candid in expressing their frustrations. In other words, higher central serotonin transmission might allow us to behave adroitly and opportunistically, being good at playing games while pursuing self-interest. We provide unique neurobiological evidence to account for individual differences of reaction to unfairness.
机译:一个人如何处理不公平的行为?长期以来,该学科已被包括哲学,心理学,经济学和生物学在内的各种学科研究。但是,我们对不公平的反应因人而异。使用最后通game博弈(UG)进行的实验经济学研究(参与者必须决定是否接受公平或不公平的要约),也表明,对不公平的反应存在很大的个体差异。然而,关于这种观察的心理和神经生物学机制知之甚少。我们结合了分子成像技术,经济学游戏和个性清单,以阐明对不公平现象的异质反应的神经生物学机制。与普遍的看法相反,在UG中,好斗的性格(冲动性或敌意性)与拒绝不公平提议的比率高有关,我们发现具有明显和平的性格(直率和信任)的人拒绝的频率更高,并以个人昂贵的方式报复。此外,背缝核中5-羟色胺转运蛋白水平低的人是诚实和信任的,因此不能容忍不公平,坦率地表达自己的挫败感。换句话说,较高的中央5-羟色胺传递可能使我们机敏和机会主义地表现出来,善于玩游戏,同时追求自身利益。我们提供独特的神经生物学证据来说明对不公平现象的个体差异。

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  • 作者单位

    Department of Psychiatry, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan,Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan,Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan,Brain Science Institute, Tamagawa University, Machida, Tokyo 194-8610, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Division of Humanities and Social Sciences, California Institute of Technology, Pasadena, CA 91125;

    Department of Psychology, Waseda University, Shinjyuku-ku, Tokyo 162-8644, Japan;

    Department of Psychology, Waseda University, Shinjyuku-ku, Tokyo 162-8644, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Department of Psychology, Waseda University, Shinjyuku-ku, Tokyo 162-8644, Japan;

    Department of Psychology, Waseda University, Shinjyuku-ku, Tokyo 162-8644, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Department of Psychiatry, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan;

    Department of Neuropsychiatry, Nippon Medical School, Bunkyo-ku, Tokyo 113-8603, Japan;

    Department of Neuropsychiatry, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

    Molecular Imaging Center, Department of Molecular Neuroimaging, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    positron emission tomography; decision-making; fairness;

    机译:正电子发射断层扫描做决定;公平;

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