Model for mitochondria damage in Parkinson disease

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Model for mitochondria damage in Parkinson disease

机译：帕金森病线粒体损伤模型

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Previous studies have shown that two Parkinson disease-related proteins, PINK1 and Parkin, promote a selective turnover of damaged mitochondria in cultured cells. But it remains unclear whether these proteins influence quality control in the typical mitochondria of dopaminergic neurons, which gradually degenerate in patients with Parkjnson disease. Jonathon Burman et al.

机译：先前的研究表明，与帕金森氏病相关的两种蛋白质PINK1和帕金森氏菌可促进培养细胞中受损线粒体的选择性更新。但尚不清楚这些蛋白是否影响多巴胺能神经元典型线粒体的质量控制，而线粒体在帕金森病患者中逐渐退化。 Jonathon Burman等。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第26期|p.10125|共1页
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson’s disease models [J] . Young Cheol Kang, Minuk Son, Sora Kang, Experimental & molecular medicine. . 2018,第8期

机译：穿透细胞的靶向线粒体的肽结合金属硫蛋白1A减轻帕金森病模型中的线粒体损伤
2. Triple herbal extract DA-9805 exerts a neuroprotective effect via amelioration of mitochondrial damage in experimental models of Parkinson’s disease [J] . Jin Seok Jeong, Ying Piao, Sora Kang, Scientific reports. . 2018,第1期

机译：三重草药提取物DA-9805通过改善帕金森氏病实验模型中的线粒体损伤发挥神经保护作用
3. Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage. [J] . Stichel CC, Zhu XR, Bader V, Human Molecular Genetics . 2007,第20期

机译：帕金森氏病的单突变和双突变小鼠模型显示出严重的线粒体损伤。
4. Mitochondrial Fragmentation Mediates MPP~+ Toxicity in Neurons: Implications for Parkinson's Disease [C] . Xinglong Wang, Mark A. Smith, George Perry, International Metallographic Society Annual meeting;Microscopy Society of America Annual Meeting;Microanalysis Society Annual meeting . 2011

机译：线粒体片段介导神经元的MPP〜+毒性：对帕金森氏病的影响
5. Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease. [D] . Xie, Weilin. 2011

机译：α-突触核蛋白在帕金森氏病的细胞和动物模型中损害线粒体的正常动力学。
6. Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson’s disease models [O] . Young Cheol Kang, Minuk Son, Sora Kang, 2018

机译：细胞穿透性人工线粒体靶向肽结合的金属硫蛋白1A减轻帕金森病模型中的线粒体损伤
7. Hepcidin ameliorates mitochondrial damage in a rat model of Parkinson's disease (P3.019) [O] . 2016

机译：肝素改善了帕金森病的大鼠模型中的线粒体损伤（P3.019）

Model for mitochondria damage in Parkinson disease

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