Bacterium expands its genetic code depending on carbon source

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Bacterium expands its genetic code depending on carbon source

机译：细菌根据碳源扩展其遗传密码

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Some archaeal and bacterial species have evolved an expanded genetic code in which the stop codon UAG can encode the noncanonical amino acid pyrrolysine (Pyl), but little is known about the Pyl regulatory system in vivo. Laure Prat et al. (pp. 21070-21075) investigated the regulation of Pyl-decoding in three bacterial species that naturally contain the gene cassette required to synthesize and genetically decode the Pyl codon.

机译：一些古细菌和细菌物种已进化出扩展的遗传密码，其中终止密码子UAG可以编码非规范氨基酸吡咯赖氨酸（Pyl），但对体内的Pyl调控系统知之甚少。 Laure Prat等。（pp。21070-21075）研究了三种细菌物种中Pyl编码的调控，这些细菌自然包含合成和遗传解码Pyl密码子所需的基因盒。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第51期|20775-20775|共1页
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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Bacterium expands its genetic code depending on carbon source

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