Protein folding near the speed limit

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Protein folding near the speed limit

机译：蛋白质折叠接近速度极限

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Cellular proteins that fail to adopt a definite shape, or "fold," can clump and contribute to conditions such as cystic fibrosis, Alzheimer's disease, and some forms of cancer. Wiktor' Banachewicz et al. (pp. 569-573) explore the mechanism of protein folding and attempt to uncover how some proteins fold efficiently within tens of microseconds, while others fold more slowly.

机译：无法采取确定的形状或“折叠”的细胞蛋白质可能会结块并导致诸如囊性纤维化，阿尔茨海默氏病和某些形式的癌症等疾病。 Wiktor'Banachewicz等。（第569-573页）探讨了蛋白质折叠的机制，并试图揭示某些蛋白质在数十微秒内如何有效折叠，而另一些蛋白质折叠得更慢的方式。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2011年第2期|p.435|共1页
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Folding Kinetics of a Naturally Occurring Helical Peptide: Implication of the Folding Speed Limit of Helical Proteins [J] . Smita Mukherjee, Pramit Chowdhury, Michelle R. Bunagan The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical . 2008,第30期

机译：天然存在的螺旋肽的折叠动力学：螺旋蛋白的折叠速度极限的含义。
2. Speed limit of protein folding evidenced in secondary structure dynamics [J] . Milo M. Lin, Omar F. Mohammed, Gouri S. Jas, Proceedings of the National Academy of Sciences of the United States of America . 2011,第40期

机译：二级结构动力学中蛋白质折叠的速度极限
3. Reaching the protein folding speed limit with large, sub-microsecond pressure jumps [J] . Charles Dumont, Tryggvi Emilsson, Martin Gruebele Nature methods . 2009,第7期

机译：大的亚微秒级压力跳变达到蛋白质折叠速度极限
4. Combining task - and data parallelism to speed up protein folding on a desktop grid platform - is efficient protein folding possible with CHARMM on the united devices metaprocessor? [C] . B. Uk, M. Taufer, T. Stricker, IEEE/ACM International Symposium on Cluster Computing and the Grid . 2003

机译：结合任务 - 和数据并行性加速桌面网格平台上的蛋白质折叠 - 在United Devices Metaprocessor上的Charmm是有效的蛋白质折叠吗？
5. Protein folding and macromolecular dynamics: Fundamental limits of length and time scales. [D] . Lin, Milo M. 2012

机译：蛋白质折叠和大分子动力学：长度和时间尺度的基本限制。
6. Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding [O] . Malwina Szczepaniak, Manuel Iglesias-Bexiga, Michele Cerminara, 2019

机译：WW结构域的超快折叠动力学揭示了氨基酸序列如何确定蛋白质折叠的速度极限
7. Speed limit of protein folding evidenced in secondary structure dynamics [O] . Lin Milo M., Mohammed Omar F., Jas Gouri S., 2011

机译：二级结构动力学中蛋白质折叠的速度极限

Protein folding near the speed limit

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