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Sleuthing the spread of disease resistance

机译:遏制疾病传播

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Tracking the slow emergence and spread of beneficial mutations that confer resistance to disease among wild animals is often a laborious task. Hence, Camille Bonneaud et al. (pp. 7866-7871) tried a different tack: The authors measured the molecular changes occurring in a wild population of birds that displayed evidence of evolutionary change over time. The authors infected two wild populations of house finches-one from Alabama and the other from Arizona-with a bacterium that causes conjunctivitis, and measured the birds' immune responses and gene expression changes upon infection. The bird population from Alabama had a 12-year history of exposure to the bacterium, thanks to an epidemic that struck the re- gion in 1994. In contrast, the Arizona population had no previous exposure to the pathogen.
机译:跟踪有益突变在野生动物中缓慢出现和传播的有益突变通常是一项艰巨的任务。因此,Camille Bonneaud等人。 (pp。7866-7871)尝试了另一种方法:作者测量了野生鸟类群体中发生的分子变化,这些分子变化显示了随着时间的推移进化变化的证据。这组作者用引起结膜炎的细菌感染了两种野生雀科动物,一种来自阿拉巴马州,另一种来自亚利桑那州,并检测了鸟类的免疫反应和感染后基因表达的变化。得益于1994年该地区的一次流行病,阿拉巴马州的鸟类有12年的接触这种细菌的历史。相反,亚利桑那州的这些种群以前没有接触过这种病原体。

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