3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2.1

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2010年第44期|p.18927-18932|共6页
• 作者

  Alina Berdichevsky; Simona Nedelcu; Konstantinos Boulias; Nicholas A. Bishop; Leonard Guarente; H. Robert Horvitz;

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• 作者单位

  Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Cardiovascular Metabolism, Novartis Institute for Biomedical Research, Cambridge, MA 02139;

  rnHoward Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139;

  rnHoward Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139;

  rnDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 Cowen and Company, 1221 Avenue of the Americas, New York, NY 10020;

  rnDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 Paul F. Glenn Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139;

  rnHoward Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 Department of Cardiovascular Metabolism, Novartis Institute for Biomedical Research, Cambridge, MA 02139;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  progeria; lipofuscin; fatty acid oxidation; sirtuins; protein deacetylation;

  机译：早衰脂褐素脂肪酸氧化;sirtuins;蛋白质脱乙酰;