A bioluminescent reporter for hydrogen peroxide

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A bioluminescent reporter for hydrogen peroxide

机译：过氧化氢的生物发光报告分子

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Animal cells produce chemical can-nonballs called reactive oxygen species (ROS) that help kill pathogens. However, when cellular ROS levels go awry, cells often hurtle toward inflammation, injury, and disease. Hydrogen peroxide (H_2O_2), a relatively long-lived ROS that penetrates cell membranes, is known to boost immune defense. But little is known about the precise effects of H_2O_2 on animal health, partly because of a dearth of tools to detect the molecule in laboratory animals. Genevieve Van de Bittner et al.

机译：动物细胞会产生化学罐头球，称为活性氧（ROS），有助于杀死病原体。但是，当细胞中的ROS水平出现异常时，细胞通常会发炎，受伤和疾病。过氧化氢（H_2O_2）是一种寿命较长的ROS，可穿透细胞膜，可增强免疫防御能力。但是对H_2O_2对动物健康的精确影响知之甚少，部分原因是缺乏用于检测实验动物中该分子的工具。 Genevieve Van de Bittner等人。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2010年第50期|p.21231|共1页
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter [J] . Genevieve C. Van de Bittner, Elena A. Dubikovskaya, Carolyn R. Bertozzi, Proceedings of the National Academy of Sciences of the United States of America . 2010,第50期

机译：化学选择性生物发光报告基因在小鼠肿瘤模型中产生过氧化氢的体内成像
2. Bioluminescent Probe for Hydrogen Peroxide Imaging in Vitro and in Vivo [J] . Wenxiao Wu, Jing Li, Laizhong Chen, Analytical chemistry . 2014,第19期

机译：用于体外和体内过氧化氢成像的生物发光探针
3. Design and Synthesis of a BODIPY‐Tetrazole Based “Off‐On” in‐Cell Fluorescence Reporter of Hydrogen Peroxide [J] . An Peng, Lewandowski Tracey M., Lin Qing Chembiochem: A European journal of chemical biology . 2018,第12期

机译：基于二己 - 四唑的“脱机”细胞荧光报道的设计与合成过氧化氢
4. USE OF BIOLUMINESCENT REPORTER BACTERA TO STUDY INVASION AND SURVIVAL WITHIN MAMMALIAN CELL LINES [C] . KL CUTTER, SM NELSON, J GREENMAN, International Symposium on Bioluminescence and Chemiluminescence . 2007

机译：使用生物发光记者细菌在哺乳动物细胞系中研究侵袭和生存
5. Bioluminescent Reporter Development and Testing for Cre-Recombinase and CRISPR/Cas9 Activity for Selectable Marker Recovery in Scheffersomyces stipitis [D] . Smith, Serenah. 2021

机译：生物发光记者的开发和测试Cre-Reobominase和Crispr / Cas9活性，用于什菲氏症患者在夏罗西氏症中选择的标记恢复
6. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter [O] . Genevieve C. Van de Bittner, Elena A. Dubikovskaya, Carolyn R. Bertozzi, 2010

机译：化学选择性生物发光报告基因在小鼠肿瘤模型中产生过氧化氢的体内成像
7. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter [O] . Van de Bittner, Genevieve C., Dubikovskaya, Elena A., Bertozzi, Carolyn R., 2010

机译：化学选择性生物发光报告基因在小鼠肿瘤模型中产生过氧化氢的体内成像
8. Molecular Probes and Bioluminescent Reporters in Ecological Optimization ofBiodegradation [R] . Sayler, G. S. 1995

机译：分子探针和生物发光记者在生物降解中的应用

A bioluminescent reporter for hydrogen peroxide

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