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A public choice framework for controlling transmissible and evolving diseases

机译:控制传染病和发展中疾病的公共选择框架

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摘要

Control measures used to limit the spread of infectious disease often generate externalities. Vaccination for transmissible diseases can reduce the incidence of disease even among the unvacci-nated, whereas antimicrobial chemotherapy can lead to the evolution of antimicrobial resistance and thereby limit its own effectiveness over time. We integrate the economic theory of public choice with mathematical models of infectious disease to provide a quantitative framework for making allocation decisions in the presence of these externalities. To illustrate, we present a series of examples: vaccination for tetanus, vaccination for measles, antibiotic treatment of otitis media, and antiviral treatment of pandemic influenza.
机译:用于限制传染病传播的控制措施通常会产生外部性。即使在未接种疫苗的人群中,传染性疾病的疫苗接种也可以减少疾病的发生,而抗微生物化学疗法可导致抗微生物药物耐药性的发展,并因此限制其自身有效性。我们将公共选择的经济学理论与传染病的数学模型相结合,为在存在这些外部性的情况下做出分配决策提供了定量框架。为了说明这一点,我们提供了一系列示例:破伤风疫苗接种,麻疹疫苗接种,中耳炎的抗生素治疗以及大流行性流感的抗病毒治疗。

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