Membrane-associated farnesylated UCH-L1 promotes α-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2009年第12期|4635-4640|共6页
• 作者

  Zhihua Liu; Robin K. Meray; Tom N. Grammatopoulos; Ross A. Fredenburg; Mark R. Cookson; Yichin Liu; Todd Logan; Peter T. Lansbury Jr.;

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• 作者单位

  Center for Neurologic Diseases, Brigham and Women's Hospital and Department of Neurology, Harvard Medical School, 65 Landsdowne Street, Cambridge, MA 02139 Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

  Center for Neurologic Diseases, Brigham and Women's Hospital and Department of Neurology, Harvard Medical School, 65 Landsdowne Street, Cambridge, MA 02139 Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

  Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

  Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

  Laboratory of Neurogenetics, National Institutes of Health, Building 35, 9000 Rockville Pike, Bethesda, MD 20892;

  Center for Neurologic Diseases, Brigham and Women's Hospital and Department of Neurology, Harvard Medical School, 65 Landsdowne Street, Cambridge, MA 02139;

  Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

  Center for Neurologic Diseases, Brigham and Women's Hospital and Department of Neurology, Harvard Medical School, 65 Landsdowne Street, Cambridge, MA 02139 Link Medicine Corporation, 161 First Street, Cambridge, MA 02142;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  farnesylation; synuclein;

  机译：法呢基化;突触核蛋白;