...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Niche partitioning in the coevolution of 2 distinct RNA enzymes
【24h】

Niche partitioning in the coevolution of 2 distinct RNA enzymes

机译：在2种不同的RNA酶共同进化中的生态位分配

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Organisms that compete for limited resources within a common environment may evolve traits that allow them to exploit distinct ecological niches, thus enabling multiple species to coexist within the same habitat. The process of niche partitioning now has been captured at the molecular level, employing the method of continuous in vitro evolution. Mixed populations of 2 different "species" of RNA enzymes were made to compete for limited amounts of one or more substrates, with utilization of the substrate being necessary for amplification of the RNA. Evolution in the presence of a single substrate led to the extinction of one or the other enzyme, whereas evolution in the presence of 5 alternative substrates led to the accumulation of mutations that allowed each enzyme to exploit a different preferred resource. The evolved enzymes were capable of sustained coevolution within a common environment, exemplifying the emergence of stable ecological niche behavior in a model system. Biochemical characterization of the 2 evolved enzymes revealed marked differences in their kinetic properties and adaptive strategies. One enzyme reacted with its preferred substrate ≈100-fold faster than the other, but the slower-reacting species produced 2- to 3-fold more progeny per reacted parent molecule. The in vitro coevolution of 2 or more species of RNA enzymes will make possible further studies in molecular ecology, including the exploration of more complex behaviors, such as predation or cooperation, under controlled laboratory conditions.
机译：在公共环境中竞争有限资源的生物可能会进化出一些特性，使它们能够利用独特的生态位，从而使多种物种在同一栖息地内共存。现在，采用连续体外进化的方法已在分子水平上捕获了小生境的分配过程。使2种不同“物种”的RNA酶的混合种群竞争有限量的一种或多种底物，其中利用底物对于扩增RNA是必需的。在单一底物存在下的进化导致一种或另一种酶的灭绝，而在5种替代底物存在下的进化导致突变的积累，从而允许每种酶利用不同的优选资源。进化的酶能够在共同的环境中持续协同进化，例证了模型系统中稳定生态位行为的出现。两种进化酶的生化特征揭示了它们的动力学特性和适应策略的显着差异。一种酶与其优选的底物发生的反应比另一种酶快约100倍，但是反应较慢的物种每个反应的亲代分子产生的后代多2至3倍。 2种或更多种RNA酶的体外协同进化将使分子生态学的进一步研究成为可能，包括在受控的实验室条件下探索更复杂的行为，例如捕食或合作。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号