...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Age at first reproduction explains rate variation in the strepsirrhine molecular clock
【24h】

Age at first reproduction explains rate variation in the strepsirrhine molecular clock

机译：初次繁殖的年龄解释了链菌素分子钟的速率变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Although the molecular clock hypothesis posits that the rate of molecular change is constant over time, there is evidence that rates vary among lineages. Some of the strongest evidence for variable molecular rates comes from the primates; e.g., the "hominoid slowdown." These rate differences are hypothesized to correlate with certain species attributes, such as generation time and body size. Here, we examine rates of molecular change in the strepsirrhine suborder of primates and test whether body size or age at first reproduction (a proxy for generation time) explains patterns of rate variation better than a null model where the molecular clock is independent of these factors. To examine these models, we analyzed DNA sequences from four pairs of recently diverged strepsirrhine sister taxa to estimate molecular rates by using sign tests, likelihood ratio tests, and regression analyses. Our analysis does not support a model where body weight or age at first reproduction strongly influences rates of molecular evolution across mitochondrial and nuclear sites. Instead, our analysis supports a model where age at first reproduction influences neutral evolution in the nuclear genome. This study supports the generation time hypothesis for rate variation in the nuclear molecular clock. Molecular clock variation due to generation time may help to resolve the discordance between molecular and paleontological estimates for divergence date estimates in primate evolution.
机译：尽管分子钟假说假设分子变化的速率随时间变化是恒定的，但有证据表明，各个谱系之间的变化速率不同。有关灵长类动物分子速率变化的最有力证据是灵长类动物。例如“类人动物减速”。假设这些速率差异与某些物种属性（例如世代时间和体型）相关。在这里，我们检查了灵长类动物的菊苣亚纲中分子变化的速率，并测试了首次繁殖时的体型或年龄（代表代时）比分子模型独立于这些因素的空模型更好地解释了速率变化的模式。 。为了检查这些模型，我们分析了四对最近发散的链菌素姐妹类群的DNA序列，以通过使用符号测试，似然比测试和回归分析来估计分子速率。我们的分析不支持这样一种模型，即初生时的体重或年龄会强烈影响跨线粒体和核部位的分子进化速率。取而代之的是，我们的分析支持一种模型，其中初生年龄会影响核基因组的中性进化。这项研究支持核分子时钟速率变化的生成时间假说。由于世代时间引起的分子钟变化可能有助于解决灵长类动物进化中发散日期估计的分子估计与古生物学估计之间的不一致。

著录项

  • 来源
  • 作者

    C.Tsantes; M. E. Steiper;

  • 作者单位

    Department of Anthropology, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10065;

    Department of Anthropology, Hunter College of the City University of New York, 695 Park Avenue, New York, NY 10065 Programs in Anthropology and Biology, Graduate Center, City University of New York, 365 Fifth Avenue, New York, NY 10016;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    evolution; primates; generation time; body size; strepsirhine;

    机译：演化;灵长类动物产生时间;身体尺寸;链霉素;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号