...
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Hierarchical computation in the canonical auditory cortical circuit
【24h】

Hierarchical computation in the canonical auditory cortical circuit

机译:典范听觉皮层回路中的分层计算

获取原文
获取原文并翻译 | 示例
           

摘要

Sensory cortical anatomy has identified a canonical microcircuit underlying computations between and within layers. This feedforward circuit processes information serially from granular to supragranular and to infragranular layers. How this substrate correlates with an auditory cortical processing hierarchy is unclear. We recorded simultaneously from all layers in cat primary auditory cortex (Al) and estimated spectrotemporal receptive fields (STRFs) and associated nonlinearities. Spike-triggered averaged STRFs revealed that temporal precision, spectrotemporal separability, and feature selectivity varied with layer according to a hierarchical processing model. STRFs from maximally informative dimension (MID) analysis confirmed hierarchical processing. Of two cooperative MIDs identified for each neuron, the first comprised the majority of stimulus information in granular layers. Second MID contributions and nonlinear cooperativity increased in supragranular and infragranular layers. The Al microcircuit provides a valid template for three independent hierarchical computation principles. Increases in processing complexity, STRF cooperativity, and nonlinearity correlate with the synaptic distance from granular layers.
机译:感觉皮层解剖学已经确定了在层之间和层内的计算基础的典型微电路。该前馈电路按顺序处理从颗粒到颗粒上和颗粒下层的信息。该底物如何与听觉皮层处理层次相关联尚不清楚。我们同时记录了猫初级听觉皮层(Al)的所有层,并估计了光谱时空感受野(STRFs)和相关的非线性。峰值触发的平均STRF显示,时间精度,光谱时可分离性和特征选择性根据分层处理模型随层而变化。来自最大信息量(MID)分析的STRF确认了分层处理。在为每个神经元确定的两个合作MID中,第一个包含颗粒层中的大多数刺激信息。第二个MID贡献和非线性合作性在颗粒上层和颗粒下层增加。 Al微电路为三个独立的分层计算原理提供了有效的模板。处理复杂性,STRF合作性和非线性的增加与到颗粒层的突触距离相关。

著录项

  • 来源
  • 作者单位

    University of California, San Francisco/University of California, Berkeley Bioengineering Graduate Group, San Francisco, CA 94143 W. M. Keck Foundation Center for Integrative Neuroscience, San Francisco, CA 94143 Coleman Memorial Laboratory, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA 94143;

    The Salk Institute for Biological Studies, La Jolla, CA 92037 and Center for Theoretical Biological Physics, University of California at San Diego, La Jolla, CA 92093;

    University of California, San Francisco/University of California, Berkeley Bioengineering Graduate Group, San Francisco, CA 94143 W. M. Keck Foundation Center for Integrative Neuroscience, San Francisco, CA 94143 Coleman Memorial Laboratory, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA 94143;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    auditory cortex; cortical laminae; information; spectrotemporal receptive field;

    机译:听觉皮层皮层信息;光谱时域;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号