Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool

Roger A. Davis; Alan D. Attie

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Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool

机译：回肠基底外侧胆汁酸转运蛋白的删除确定了调节胆汁酸池的细胞前哨

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Bile acids are potent detergents and are essential for efficient digestion and absorption of dietary fat. Bile acids are synthesized by the liver from cholesterol, excreted into bile, and stored in the gallbladder. After ingestion of a fat-containing diet

机译：胆汁酸是有效的清洁剂，对于有效消化和吸收膳食脂肪至关重要。胆汁酸是由肝脏从胆固醇中合成的，排泄到胆汁中，并储存在胆囊中。摄入含脂肪饮食后

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第13期|4965-4966|共2页
作者
Roger A. Davis; Alan D. Attie;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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1. Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids [J] . Masaaki Miyata, Hiroki Yamakawa, Kenjiro Hayashi, European Journal of Pharmacology: An International Journal . 2014,第Null期

机译：通过胆汁酸诱导的泛素依赖性蛋白质降解，肠道顶端依赖性胆汁酸转移蛋白水平下调
2. Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids [J] . MiyataM., YamakawaH., HayashiK., European Journal of Pharmacology: An International Journal . 2013,第1a3期

机译：回肠根尖钠依赖性胆汁酸转运蛋白水平通过胆汁酸诱导的泛素依赖性蛋白降解而下调
3. Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits. [J] . Xu G, Shneider BL, Shefer S, Journal of Lipid Research . 2000,第2期

机译：回肠胆汁酸运输对胆固醇喂养的大鼠和兔子的胆汁酸池，合成和血浆胆固醇水平的调节不同。
4. Manipulating the Bile Acid Pool Regulates Cyp7a1 By Changing Fxr Activation [C] . G. Xu, G. Salen, L. Pan, Falk Symposium . 2003

机译：操纵胆汁酸池通过改变FXR激活来调节CYP7A1
5. Ileal bile acid transporter inhibitors: A search for new, alternative cholesterol-lowering drugs using methods in pharmacology and information science. [D] . Root, Carolyn. 2005

机译：回肠胆汁酸转运蛋白抑制剂：使用药理学和信息科学方法寻找新的替代性降胆固醇药物。
6. Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool [O] . Roger A. Davis, Alan D. Attie 2008

机译：回肠基底外侧胆汁酸转运蛋白的删除确定了调节胆汁酸池的细胞前哨
7. Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool [O] . Davis, Roger A., Attie, Alan D. 2008

机译：回肠基底外侧胆汁酸转运蛋白的删除确定了调节胆汁酸池的细胞前哨

Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool

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