MiR-15a and miR-16-1 cluster functions in human leukemia

George A. Calin; Amelia Cimmino; Muller Fabbri; Manuela Ferracin; Sylwia E. Wojcik; Masayoshi Shimizu; Cristian Taccioli; Nicola Zanesi; Ramiro Garzon; Rami I. Aqeilan; Hansjuerg Alder; Stefano Volinia; Laura Rassenti; Xiuping Liu; Chang-gong Liu; Thomas J. Kipps; Massimo Negrini; Carlo M. Croce

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MiR-15a and miR-16-1 cluster functions in human leukemia

机译：miR-15a和miR-16-1在人白血病中的功能簇

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摘要

MicroRNAs (miRNAs) are short noncoding RNAs regulating gene expression that play roles in human diseases, including cancer. Each miRNA is predicted to regulate hundreds of transcripts, but only few have experimental validation. In chronic lymphocytic leuk

机译：微小RNA（miRNA）是调节基因表达的短非编码RNA，在人类疾病（包括癌症）中起作用。每种miRNA预计会调控数百种转录本，但只有少数经过实验验证。在慢性淋巴细胞性白血病

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第13期|5166-5171|共6页
作者
George A. Calin; Amelia Cimmino; Muller Fabbri; Manuela Ferracin; Sylwia E. Wojcik; Masayoshi Shimizu; Cristian Taccioli; Nicola Zanesi; Ramiro Garzon; Rami I. Aqeilan; Hansjuerg Alder; Stefano Volinia; Laura Rassenti; Xiuping Liu; Chang-gong Liu; Thomas J. Kipps; Massimo Negrini; Carlo M. Croce;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
cancer; microRNA; targets;

机译：癌症;微小RNA;目标;

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1. A novel marsupial pri-miRNA transcript has a putative role in gamete maintenance and defines a vertebrate miRNA cluster paralogous to the miR-15a/miR-16-1 cluster [J] . Phil Chi Khang Au, Stephen Frankenberg, Lynne Selwood, Reviews of Reproduction . 2011,第4期

机译：一种新颖的有袋动物pri-miRNA转录本在配子维持中具有推定作用，并定义了与miR-15a / miR-16-1簇同源的脊椎动物miRNA簇
2. A novel marsupial pri-miRNA transcript has a putative role in gamete maintenance and defines a vertebrate miRNA cluster paralogous to the miR-15a/miR-16-1 cluster [J] . Phil Chi Khang Au, Stephen Frankenberg, Lynne Selwood, Reproduction: The official journal of the Society for the Study of Fertility . 2011,第4期

机译：一种新颖的有袋动物pri-miRNA转录本在配子维持中具有推定作用，并定义了与miR-15a / miR-16-1簇同源的脊椎动物miRNA簇
3. The Role of miR-15a and miR-16-1 in the Pathogenesis of Chronic Lymphocytic Leukemia, and the Importance of microRNAs in Targeted Therapies [J] . A. Calva-Lopez, Carlos A. Tirado The Journal of the Association of Genetic Technologists . 2018,第3期

机译：miR-15a和miR-16-1在慢性淋巴细胞白血病发病机制中的作用，以及MicroRNA在靶向疗法中的重要性
4. Functional Evaluation of Anticancer Drugs in Human Leukemia Cells Based on Metabolic Profiling Technique [C] . Daisuke Miura, Yoshinori Fujimura, Hirofumi Tachibana, Annual and International Meeting of the Japanese Association for Animal Cell Technology . 2010

机译：基于代谢分析技术的人白血病细胞抗癌药物的功能评价
5. Isolation and functional mapping of Human T-cell Leukemia Virus Type 1 Tax oncoprotein DNA-damage complexes. [D] . Durkin, Sarah Saionz. 2006

机译：人类T细胞白血病病毒1型税收癌蛋白DNA损伤复合物的分离和功能定位。
6. MiR-15a and miR-16-1 cluster functions in human leukemia [O] . George A. Calin, Amelia Cimmino, Muller Fabbri, 2008

机译：miR-15a和miR-16-1在人白血病中的功能簇
7. MiR-15a and miR-16-1 cluster functions in human leukemia [O] . Calin, George A., Cimmino, Amelia, Fabbri, Muller, 2008

机译：miR-15a和miR-16-1在人白血病中的功能簇

MiR-15a and miR-16-1 cluster functions in human leukemia

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