Mechanism of Cu~+-transporting ATPases: Soluble Cu~+ chaperones directly transfer Cu~+ to transmembrane transport sites

Manuel Gonzalez-Guerrero; Jose M. Argiiello

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Mechanism of Cu~+-transporting ATPases: Soluble Cu~+ chaperones directly transfer Cu~+ to transmembrane transport sites

机译：Cu〜+转运ATPase的机制：可溶性Cu〜+分子伴侣直接将Cu〜+转运至跨膜转运位点

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As in other P-type ATPases, metal binding to transmembrane metal-binding sites (TM-MBS) in Cu~+-ATPases is required for enzyme phosphorylation and subsequent transport. However, Cu~+ does not access Cu~+-ATPases in a free (hydrated) form but is bound to a

机译：与其他P型ATP酶一样，Cu〜+ -ATPase中的金属必须与跨膜金属结合位点（TM-MBS）结合才能进行酶的磷酸化和随后的转运。但是，Cu〜+不能以游离（水合）形式访问Cu〜+ -ATPase，而是与

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第16期|5992-5997|共6页
作者
Manuel Gonzalez-Guerrero; Jose M. Argiiello;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
CopA; CopZ; Cu homeostasis; Cu-ATPase; metal binding;

机译：COPA;CopZ;具有体内平衡;铜ATP酶金属结合;

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专利

1. Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA [J] . Andrew?M. Hemmings, Chloe Singleton, Liang Zhou, The biochemical journal . 2009,第3期

机译：分子伴侣CopZ及其同源的Cu（I）转运P型ATPase，CopA之间的Cu（I）簇转移的机械性见解
2. Mechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopA. [J] . Singleton C, Hearnshaw S, Zhou L, The Biochemical Journal . 2009,第3期

机译：机械洞察分子伴侣CopZ和其关联的Cu（I）传输P型ATP酶CopA之间的Cu（I）簇转移。
3. Sequence of a Menkes-type Cu-transporting ATPase from Rat C6 glioma cells: Comparison of the rat protein with other mammalian Cu-transporting ATPases [J] . Yongchang Qian, Evelyn Tiffany-Castiglioni, Edward D. Harris Molecular and Cellular Biochemistry: An International Journal for Chemical Biology . 1998,第1a2期

机译：大鼠C6胶质瘤细胞中Menkes型铜转运ATPase的序列：大鼠蛋白与其他哺乳动物铜转运ATPase的比较
4. A role of B-site cation on structural and transport properties of La_2BMnO_6 (B= Cr, Fe, Co, Ni, Cu, Zn) double perovskites [C] . Javed Ahmad, Mozammal Iqbal, Jamshaid Alam Khan, iiScience International Conference . 2020

机译：B型阳离子对La_2bmno_6（b = Cr，Fe，Co，Ni，Cu，Zn）双钙钛矿的结构和运输性能的作用
5. Effects of Rare Earth Metal Additions on the Performance of Al-Cu and Al-Si-Cu Based Alloys =Effets de l'ajout des métaux terres rares sur les performances des alliages Al-Cu et Al-Si-Cu [D] . Mahmoud, Mohamed Gamal Ramadan. 2018

机译：稀土金属添加对Al-Cu和Al-Si-Cu基合金性能的影响=加入稀有金属对Al-Cu和Al-Si-Cu合金性能的影响
6. Mechanism of Cu+-transporting ATPases: Soluble Cu+ chaperones directly transfer Cu+ to transmembrane transport sites [O] . Manuel González-Guerrero, José M. Argüello 2008

机译：Cu +转运ATPase的机制：可溶性Cu +分子伴侣直接将Cu +转运到跨膜转运位点
7. Mechanism of Cu+-transporting ATPases: Soluble Cu+ chaperones directly transfer Cu+ to transmembrane transport sites [O] . González-Guerrero, Manuel, Argüello, José M. 2008

机译：Cu +转运ATPase的机制：可溶性Cu +分子伴侣直接将Cu +转运到跨膜转运位点

Mechanism of Cu~+-transporting ATPases: Soluble Cu~+ chaperones directly transfer Cu~+ to transmembrane transport sites

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