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Gender Differences In Human Cortical Synaptic Density

机译:人体皮质突触密度的性别差异

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摘要

Certain cognitive functions differ in men and women, although the anatomical and functional substrates underlying these differences remain unknown. Because neocortical activity is directly related with higher brain function, numerous studies have focused on the cerebral cortex when searching for possible structural correlates of cognitive gender differences. However, there are no studies on possible gender differences at the synaptic level. In the present work we have used stereological and correlative light and electron microscopy to show that men have a significantly higher synaptic density than women in all cortical layers of the temporal neocor-tex. These differences may represent a microanatomical substrate contributing to the functional gender differences in brain activity.
机译:男女的某些认知功能有所不同,尽管造成这些差异的解剖学和功能基础仍然未知。由于新皮层活动与更高的脑功能直接相关,因此在寻找认知性别差异的可能结构相关性时,许多研究都集中在大脑皮层上。但是,目前尚无关于突触水平性别差异的研究。在目前的工作中,我们使用了立体和相关的光镜和电子显微镜,以显示在颞叶新皮层的所有皮质层中,男性的突触密度明显高于女性。这些差异可能代表了有助于人体活动的性别差异的微观解剖结构。

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