Innate response to self-antigen significantly exacerbates burn wound depth

Freeman Suber; Michael C. Carroll; Francis D. Moore Jr.

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Innate response to self-antigen significantly exacerbates burn wound depth

【24h】

Innate response to self-antigen significantly exacerbates burn wound depth

机译：对自身抗原的先天反应显着加剧了烧伤创口深度

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A major component of burn injury is caused by additional local damage from acute inflammation. Using a scald burn model in mice, we find that this part of the injury is dependent on recognition of self-antigen by specific natural IgM, leading to activation of the complement system. We propose that the depth of a burn wound is a sum of the thermal energy applied and of the degree of host inflammatory response.

机译：烧伤的主要成分是急性炎症引起的其他局部损害。使用小鼠烫伤模型，我们发现这部分损伤取决于特定天然IgM对自身抗原的识别，从而导致补体系统的激活。我们建议烧伤创面的深度是所施加的热能与宿主炎症反应程度的总和。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |2007年第10期|p.3973-3977|共5页
作者
Freeman Suber; Michael C. Carroll; Francis D. Moore Jr.;
展开▼
作者单位

Harvard Medical School, Boston, MA 02115;

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词
complement; natural IgM; trauma; wound physiology;

机译：补体;天然IgM;创伤;伤口生理;

相似文献

外文文献
中文文献
专利

1. Interactions of systemic immune response and local wound healing in different burn depths: an experimental study on rats. [J] . Sakallioglu AE, Basaran O, Karakayali H, Journal of burn care & research: official publication of the American Burn Association . 2006,第3期

机译：不同烧伤深度的全身免疫反应与局部伤口愈合的相互作用：对大鼠的实验研究。
2. Response to Letter to the Editor: Modulation of AQP-3 in burn wound: Comment on "Epidermal aquaporin-3 is increased in the cutaneous burn wound" [J] . Sebastian R., Chau E., Fillmore P., Burns: Including Thermal Injury . 2015,第7期

机译：对致编辑的信的回复：烧伤创面中的AQP-3调节：评论“表皮水通道蛋白3在皮肤烧伤创面中增加”
3. Assessment of burn depth and burn wound healing potential. [J] . Monstrey S, Hoeksema H, Verbelen J, Burns: Including Thermal Injury . 2008,第6期

机译：评估烧伤深度和烧伤创面的愈合潜力。
4. Infrared imaging of burn wounds to determine burn depth [C] . Andrew G. Hargroder, Baton Rouge General Regional Burn Ctr., Baton Rouge, Conference on infrared technology and applications . 1999

机译：烧伤伤口的红外成像以确定烧伤深度
5. Forward-looking Infrared Image Analysis of Whole Burn Area at Early Time Points to Predict Ultimate Burn Depth of Partial and Full Thickness Burns [D] . Musillo, Michael. 2019

机译：在早期烧伤区域的整个烧伤区域的前瞻性红外图像分析预测部分和全厚度燃烧的最终烧伤深度
6. Innate response to self-antigen significantly exacerbates burn wound depth [O] . Freeman Suber, Michael C. Carroll, Francis D. Moore Jr. 2007

机译：对自身抗原的先天反应显着加剧了烧伤创口深度
7. Innate response to self-antigen significantly exacerbates burn wound depth [O] . Suber, Freeman, Carroll, Michael C., Moore, Francis D. 2007

机译：对自身抗原的先天反应显着加剧了烧伤创口深度

Innate response to self-antigen significantly exacerbates burn wound depth

摘要

著录项

相似文献

相关主题

期刊订阅