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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Resting-state networks in the infant brain
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Resting-state networks in the infant brain

机译：婴儿大脑中的静止状态网络

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In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as system-wide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is currently unknown. Therefore, we used functional MRI to map patterns of resting-state activity in infants during sleep. We found five unique resting-states networks in the infant brain that encompassed the primary visual cortex, bilateral sensorimotor areas, bilateral auditory cortex, a network including the precuneus area, lateral parietal cortex, and the cerebellum as well as an anterior network that incorporated the medial and dorsolateral prefrontal cortex. These results suggest that resting-state networks driven by spontaneous signal fluctuations are present already in the infant brain. The potential link between the emergence of behavior and patterns of resting-state activity in the infant brain is discussed.
机译：在没有任何明显的任务表现的情况下，已经显示出自发的，固有的大脑活动被表示为成年大脑中的全系统的静止状态网络。但是，目前尚不知道通过人脑神经元发育达到成人静止状态活动模式的途径。因此，我们使用功能性MRI来绘制婴儿在睡眠期间的休息状态活动模式。我们在婴儿脑中发现了五个独特的静止状态网络，包括主要视觉皮层，双侧感觉运动区域，双侧听觉皮层，包括前神经区域，顶顶外侧皮层和小脑的网络以及合并了前神经网络的前部网络。内侧和背外侧前额叶皮层。这些结果表明，婴儿大脑中已经存在由自发信号波动驱动的静止状态网络。讨论了行为的出现与婴儿大脑中静止状态活动模式之间的潜在联系。

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