Germ cells carry the epigenetic benefits of grandmother's diet

Craig A. Cooney

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Germ cells carry the epigenetic benefits of grandmother's diet

机译：生殖细胞具有祖母饮食的表观遗传优势

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Environmental influences on epi-genetics are important for understanding the mechanisms and inheritance of biological variation. Some of the best models for mammalian epigenetics are the yellow alleles of agouti in mice. Alleles such as A~(vy) produce readily distinguished agouti, yellow, and mottled coat-color epigenetic phenotypes. Dietary and genetic variations during development affect the epigenetic phenotypes of offspring. Little is known regarding the gesta-tional timing of dietary treatments to affect epigenetics.

机译：环境对表观遗传学的影响对于理解生物学变异的机制和遗传至关重要。哺乳动物表观遗传学的一些最佳模型是老鼠中的刺豚鼠黄色等位基因。等位基因，例如A〜（vy）产生容易区分的刺豚鼠，黄色和斑驳的外壳颜色表观遗传表型。发育过程中的饮食和遗传变异会影响后代的表观遗传表型。关于影响表观遗传学的饮食治疗的时机知之甚少。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2006年第46期|p.17071-17072|共2页
作者
Craig A. Cooney;
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作者单位

Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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2. Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells [J] . Kristensen D.G., Skakkeb?k N.E., Rajpert-De Meyts E., The international journal of developmental biology . 2013,第2a4期

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4. Germ Line, Stem Cells, and Epigenetic Reprogramming [C] . M.A. SURANI, G. DURCOVA-HILLS, P. HAJKOVA, Cold Harbor Symposium on Quantitative Biology . 2008

机译：细菌线，干细胞和表观遗传重编程
5. Primordial Germ Cell Differentiation in Vitro: A Model for Understanding Epigenetic Reprogramming and Genome-Wide DNA Demethylation in Mouse Primordial Germ Cells. [D] . Vincent, John James. 2013

机译：原始生殖细胞的体外分化：一种模型，用于了解小鼠原始生殖细胞中的表观遗传重编程和全基因组DNA去甲基化。
6. Germ cells carry the epigenetic benefits of grandmothers diet [O] . Craig A. Cooney 2006

机译：生殖细胞具有祖母饮食的表观遗传优势
7. Germ cells carry the epigenetic benefits of grandmother's diet [O] . Cooney, Craig A. 2006

机译：生殖细胞具有祖母饮食的表观遗传优势

Germ cells carry the epigenetic benefits of grandmother's diet

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