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Generalist genes and learning disabilities

机译:通才基因与学习障碍

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The authors reviewed recent quantitative genetic research on learning disabilities that led to the conclusion that genetic diagnoses differ from traditional diagnoses in that the effects of relevant genes are largely general rather than specific. This research suggests that most genes associated with common learning disabilities-language impairment, reading disability, and mathematics disability-are generalists in 3 ways. First, genes that affect common learning disabilities are largely the same genes responsible for normal variation in learning abilities. Second, genes that affect any aspect of a learning disability affect other aspects of the disability. Third, genes that affect one learning disability are also likely to affect other learning disabilities. These quantitative genetic findings have far-reaching implications for molecular genetics and neuroscience as well as psychology.
机译:作者回顾了最近有关学习障碍的定量遗传研究,得出的结论是,遗传诊断与传统诊断的不同之处在于相关基因的作用在很大程度上是通用的而不是特异性的。这项研究表明,与常见学习障碍相关的大多数基因-语言障碍,阅读障碍和数学障碍-在3种方面都是通才。首先,影响普通学习障碍的基因与负责学习能力正常变异的基因基本相同。第二,影响学习障碍的任何方面的基因都会影响障碍的其他方面。第三,影响一种学习障碍的基因也可能影响另一种学习障碍。这些定量的遗传发现对分子遗传学,神经科学以及心理学有深远的影响。

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