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Puberty moderates genetic influences on disordered eating

机译：青春期缓解饮食失调的遗传影响

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Background. Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of the present study therefore was to directly examine this possibility by investigating whether pubertal development moderates genetic influences on disordered eating. Method. Participants were 510 female adolescent twins from the Minnesota Twin Family Study. Disordered eating was measured with the Total Score of the Minnesota Eating Behavior Survey, while pubertal status was assessed with the Pubertal Development Scale. Results. Consistent with our hypothesis, model-fitting indicated significant increases in genetic influence on disordered eating with advancing pubertal development. Conclusions. These findings suggest that puberty influences the expression of genes for disordered eating.
机译：背景。以前的研究表明，青春期女孩对青春期饮食失调的遗传影响可能更大。尽管这些发现与青春期激活对饮食失调的遗传影响相一致，但早期的研究无法直接检验这一假设。因此，本研究的目的是通过研究青春期发育是否减轻饮食失调的遗传影响来直接检验这种可能性。方法。参加者是来自明尼苏达州双胞胎家庭研究的510名女性青春期双胞胎。饮食失调是通过明尼苏达州饮食行为调查的总分来衡量的，而青春期的状态是通过青春期发育量表来评估的。结果。与我们的假设一致，模型拟合表明随着青春期的发展，遗传对无序饮食的影响显着增加。结论。这些发现表明，青春期影响饮食失调基因的表达。

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